+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immunohistochemical comparison of transscleral continuous wave 1064-Nd:YAG laser retinopexy and cryoretinopexy

, : Immunohistochemical comparison of transscleral continuous wave 1064-Nd:YAG laser retinopexy and cryoretinopexy. Retina 14(1): 51-58

Background: Transcleral retinopexy may be applied with either a cryoprobe or the newer contact laser delivery systems. Tissue responses to these modalities are studied. Methods: Transcleral 1064-nm continuous wave neodymium-ytrium-aluminum garnet (CW Nd:YAG) laser retinopexy lesions were compared with retinopexy lesions produced by a cryoprobe in a pigmented rabbit model. Equatorial transcleral CW Nd:YAG laser retinopexy or cryoretinopexy was applied. Rabbits were killed 1 day, 3 days, 1 week, or 1 month after treatment. Hematoxylin and eosin stains and immunohistochemical studies were conducted to determine the level of retinal damage and glial reaction. Antibodies against Muller cells (vimentin and glial fibrillary acidic protein), astrocytes (glial fibrillary acidic protein and S-100 protein), retinal pigment epithelial (RPE) cells (cytokeratin 8, 18, and 19 (5D3)), and macrophages (HAM 56) were used. Results: Lesions produced by cryotherapy showed significant overlying retinal destruction with intravitreal RPE cell (5D3 positive) migration. Lesions produced by lanocytes and RPE. Marked expression of both glial fibrillary acidic protein and vimentin epitopes with a normal expression of S-100 was seen in the chronic lesion made with cryotherapy and with less intensity in lesions made with CW Nd:YAG laser. retinal Muller cell reaction occurred in lesions formed by both cryotherapy and laser as demonstrated by immunohistochemical studies.


PMID: 8016463

DOI: 10.1097/00006982-199401000-00012

Other references

Parisi, G.; Francesco, M. de; Medale, F.; Scappini, F.; Mecatti, M.; Kaushik, S.J.; Poli, B.M., 2004: Effect of total replacement of dietary fish meal by plant protein sources on early postmortem changes in the biochemical and physical parameters of rainbow trout. Sterile rainbow trout Oncorhynchus mykiss were grouped into two and fed either of the two isoproteic (49% CP) and isoenergetic (21 kJ/g digestible energy) diets containing different protein sources. One diet contained fish meal (FM) while the seco...

Ashurst, J.V.; Wasson, M.N.; Hauger, W.; Fritz, W.T., 2010: Pathophysiologic mechanisms, diagnosis, and management of dapsone-induced methemoglobinemia. Dapsone is a leprostatic agent commonly prescribed for the treatment of patients with leprosy, malaria, and a variety of blistering skin diseases, including dermatitis herpetiformis. Methemoglobinemia, a potentially life-threatening condition in w...

Lee, S.C.; Johnson, H., 1975: Multiple nodular pulmonary amyloidosis. A case report and comparison with diffuse alveolar-septal pulmonary amyloidosis. A case of multiple nodular pulmonary amyloidosis in a 54-year-old Caucasian man is presented. Discrete symptomless radiodensities had developed in this patient's lungs within a period of three years, leading to a suspicion of a neoplastic pro...

Powell Wayne G.; Carmichael D.M.; Hodgson C.J., 1994: Conditions and relative timing of metamorphism during the evolution of the southern Abitibi greenstone belt. Program with Abstracts - Geological Association of Canada(Mineralogical Association of Canada(Canadian Geophysical Union, Joint Annual Meeting 19: 90

Aoki, T.; Uchida, K., 1990: Enhanced formation of 2-phenyl-ethanol in Zygosaccharomyces rouxii due to prephenate dehydrogenase deficiency. Agricultural and Biological Chemistry 54: 3-4

Strobel, A.; Zimmermann, J.; Schmitz, A.; Reuter, M.; Lis, S.; Windmann, S.; Kirsch, P., 2011: Beyond revenge: neural and genetic bases of altruistic punishment. It is still debated how altruistic punishment as one form of strong reciprocity has established during evolution and which motives may underlie such behavior. Recent neuroscientific evidence on the activation of brain reward regions during altruis...

Kang, H.Joo.; Middleditch, M.; Proft, T.; Baker, E.N., 2010: Isopeptide bonds in bacterial pili and their characterization by X-ray crystallography and mass spectrometry. Pili are long, filamentous protein assemblies which extend from the surfaces of many bacteria, and mediate their adhesion to host cells and other matrices. For pathogenic bacteria they are critical to colonization and infection. Whereas the pili o...

Ferry, O., 2004: Forests for water - a European perspective?. Water policy is changing on a European scale with the implementation of the Water Framework Directive (WFD). This Directive aims to achieve a 'good ecological status' of water through appropriate pollution control and land management and...

Pettersson, S.; Jonsson, O.; Sivertsson, R.; Säve-Söderbergh, J.; Zachrisson, B.E., 1977: Transurethral stone extraction with a vibrating basket catheter. In a recent in vitro study, mechanical vibration was shown to facilitate, considerably, both the passing of a basket catheter beyond an artificial ureteral stone as well as the extraction of a calculus. Therefore, a device by which vibration can b...

Rodesano, A.J., 1970: Disimpaction: using a pin as a method of attachment. Dental Practitioner and Dental Record 21(2): 58-61