+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immunohistochemical demonstration of androgen receptors in human salivary glands

, : Immunohistochemical demonstration of androgen receptors in human salivary glands. Archives Of Oral Biology. 38(4): 299-302

Androgen receptors were demonstrated in human salivary glands by immunohistochemistry using polyclonal antibodies. Fresh, clinically healthy salivary gland samples (two from minor, seven from parotid and eight from submandibular glands) of both sexes were used. Frozen tissue sections were incubated with the antibody against human androgen receptor and visualized by an indirect immunoperoxidase technique. Androgen receptors could be detected in all salivary tissues studied. Positive staining was confined to nuclei of almost all acinar cells as well as to the majority of nuclei in ductal cells. Very few of the nuclei of connective tissue and endothelial cells stained positively. The presence of androgen receptors in human salivary glands suggests possible direct effects of androgen on these tissues.


PMID: 8517801

DOI: 10.1016/0003-9969(93)90136-a

Other references

Chou, R.; Carson, S.; Chan, B.K.S., 2012: Pegylated interferons for chronic hepatitis C virus infection: an indirect analysis of randomized trials. Dual therapy with pegylated interferon and ribavirin is recommended for patients with chronic hepatitis C virus infection who meet criteria for treatment, but it is unclear whether pegylated interferon alfa-2a or pegylated interferon alfa-2b is mo...

Kluger, M.A.; Nosko, A.; Ramcke, T.; Goerke, B.; Meyer, M.C.; Wegscheid, C.; Luig, M.; Tiegs, G.; Stahl, R.A.K.; Steinmetz, O.M., 2016: RORγt expression in Tregs promotes systemic lupus erythematosus via IL-17 secretion, alteration of Treg phenotype and suppression of Th2 responses. Clinical and Experimental Immunology: -

Cosgrove, G.E.; Selby, P.B.; Upton, A.C.; Mitchell, T.J.; Steele, M.H.; Russell, W.L., 1993: Lifespan and autopsy findings in the first-generation offspring of X-irradiated male mice. Male mice of the C3Hf strain were exposed to 600 R of acute X-rays, and, along with unirradiated control males, mated with 101-strain females. The offspring of the treated males were all conceived more than 7 weeks after irradiation thereby ensuri...

Dodd, H.F.; Hudson, J.L., 2011: Parent-child CBT reduces anxiety disorders among children aged 4-7 years. Evidence-Based Mental Health 14(1): 18-18

Tsukershtein, O.E.; Kupsik, B.M., 1959: Certain variants of the hemopoietic system in diphyllobothriasis. Problemy Gematologii i Perelivaniia Krovi 4(7): 49-52

Cowan, James A., 2002: Metalloligands for cleaving nucleic acids. Transition metal complexes, referred to hereinafter as "metalloligands", that catalyze the degradation of DNA and the cleavage of RNA at select sites are provided. In one embodiment, the metalloligand has the following structure: ##STR1#...

Ellis, Be, 1982: Selection of chemically-variant plant cell lines for use in industry and agriculture Secondary metabolism proline, osmotic stress, resistance. Application of plant cell and tissue culture to agriculture and industry DT Tomes et al: 0

Brozek, J.; Samochowiec, E.; Tomala, J.; Brudnik, A., 1980: Course of pregnancy and labor after treatment of various cervical diseases by means of low temperatures. Ginekologia Polska 51(3): 221-227

Kaempchen T.; Moddelmog G.; Schulz D.; Seitz G., 1988: Cyclopenta c pyran and its 6 tert butyl derivatives. Three-step syntheses of the hitherto unknown cyclopenta[c]pyran (2) and its 6-tert-butyl derivative 12 are described. The 1H-NMR, 13C-NMR, and electronic spectra of the lemon-yellow isooxalenes are compared with those of other pseudoazulenes.

Stańczak, A.; Pakulska, W.; Pietrzak, B.; Lewgowd, W., 2001: Comparison of pharmacophore cinnoline and quinoline systems on the basis of computer calculation and pharmacological screening of their condensed systems. A series of new pyrimido(5,4-c)quinoline derivatives were prepared to compare the pharmacophore systems of cinnoline and quinoline. These compounds were obtained by the cyclocondensation of appropriately substituted 4-amino-3-quinolinecarboxylic a...