+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immunohistochemical detection of estrogen and progesterone receptors in endometriotic tissue. A comparative study of paraffin embedded and fresh frozen tissues

, : Immunohistochemical detection of estrogen and progesterone receptors in endometriotic tissue. A comparative study of paraffin embedded and fresh frozen tissues. Archives of Gynecology and Obstetrics 255(4): 181-187

30 formalin-fixed and paraffin embedded and 20 fresh frozen samples of endometriotic tissue were analysed immunohistochemically for the concentration of estrogen and progesterone receptors. In the formalin-fixed and paraffin embedded group only 37% of the samples were estrogen receptor positive whereas 63% were receptor negative. In contrast, we found that 67% of the samples had a positive progesterone receptor status. In the fresh frozen group 60% of endometriotic tissues were estrogen receptor positive and 75% of the tissues had a positive progesterone receptor status. We could not find any correlation between the site or severity of the endometriosis or the hormonal receptor status. We were able to demonstrate that the immunohistochemical detection of hormonal receptors in endometriotic tissues is possible and that better results were obtained if fresh frozen rather than formalin-fixed and paraffin embedded tissues were analyzed.


PMID: 7695364

Other references

Charter, R.A., 2003: A breakdown of reliability coefficients by test type and reliability method, and the clinical implications of low reliability. The author presented descriptive statistics for 937 reliability coefficients for various reliability methods (e.g., alpha) and test types (e.g., intelligence). He compared the average reliability coefficients with the reliability standards that ar...

Razzaghi, M.Reza.; Afshar, L., 2017: A conceptual model of physician-patient relationships: a qualitative study. In any clinical encounter, an effective physician-patient relationship is necessary for achieving the desired outcome. This outcome is successful treatment, and therefore, the relationship should be a healing one. In addition, in the Islamic view,...

Goodson, J.L., 2012: Nonapeptides are not just for bonding: a response to van Anders et al. (2011). Psychoneuroendocrinology 37(3): 444-5; Author Reply 445

Zhang, L.; Su, W.; Zhao, J., 2016: Risk factors of perioperative blood loss in elderly patients receiving proximal femur locking compression plate fixation for intertrochanteric fractures. To analyze the risk factors of perioperative blood loss in elderly patients with intertrochanteric fractures treated with proximal femur locking compression plate (PFLCP) fixation. A retrospective analysis was carried out in an cohort of 178 elder...

Van Vollenhoven, R.F.; Engleman, E.G.; Mcguire, J.L., 1994: An open study of dehydroepiandrosterone in systemic lupus erythematosus. Objective: To determine if dehydroepiandrosterone (DHEA) has clinical benefits in patients with systemic lupus erythematosus (SLE). Methods: Ten female patients with mild to moderate SLE and various disease manifestations were given DHEA (200 mg/d...

Sharma, A., 2003: First records of spoon-billed sandpiper Calidris pygmeus in the Indian Sundarbans delta, west Bengal. Forktail. August; 19: 136-137

Chislett, S.P.; Liming, B.J.; Rogers, D.J., 2016: Dystrophic calcification: A rare pediatric parotid mass. Dystrophic calcification, the ectopic deposition of calcium in previously damaged or inflamed tissues, is an uncommon finding in the head and neck. Only a few cases have been reported in the parotidomasseteric region, and all of them have been loc...

Perelman, A.Y.; Shifrin, K.S., 1980: Improvements to the spectral transparency method for determining particle-size distribution. The previously developed spectral transparency method is improved in two ways: (a) A calculation scheme is developed that enables the consideration of light dispersion within a substance. We abandon the assumption that m(nu) = const and develop a...

Brotzen Fritz, 1933: Die silurischen und devonischen Fischvorkommen in Westpodolien I. Descriptions of Silurian and Devonian fishes (Pteraspidae) from western Podolia; several new species and one new variety described.

Pilotti, S.; Patriarca, C.; Lombardi, L.; Scopsi, L.; Rilke, F., 1992: Well-differentiated neuroendocrine carcinoma of the lung: a clinicopathologic and ultrastructural study of 10 cases. The clinico-pathologic characteristics of 10 resected pulmonary tumors, which proved to be well-differentiated neuroendocrine carcinomas (WDNC) on the basis of light microscopic, immunocytochemical, ultrastructural and immunoelectron microscopic i...