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Immunohistochemical detection of pancreatic secretory trypsin inhibitor (PSTI) in urothelial cancer


, : Immunohistochemical detection of pancreatic secretory trypsin inhibitor (PSTI) in urothelial cancer. Acta Medica et Biologica 41(2): 109-112

Pancreatic secretory trypsin inhibitor (PSTI), a specific trypsin inhibitor secreted by acinar cells of pancreas, also acts as a growth factor. PSTI in various cancers has been reported to be associated with tumor invasiveness and pathological malignancy; however, such studies in urological cancers have not yet been performed. We therefore examined the expression of PSTI in fresh frozen specimens of urothelial cancers immunohistochemically, using a polyclonal antibody.

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