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Immunohistochemical detection of prostaglandin I-2 synthase in various calcified tissue-forming cells in rat


, : Immunohistochemical detection of prostaglandin I-2 synthase in various calcified tissue-forming cells in rat. Archives Of Oral Biology. 38(1): 31-36

Localization of prostaglandin (PG) I-2 synthase immunoreactivity was examined in demineralized sections of rat pulpal, periodontal and skeletal tissues using isn-1, a monoclonal antibody raised against the enzyme. Various calcified tissue-forming cells, i.e. odontoblasts, osteoblasts, osteocytes, cementoblasts, cementocytes and chondrocytes, were similarly immunoreactive for PGI-2 synthase, suggesting that they are capable of producing PGI-2. In odontoblasts and chondryocytes, the reactivity increased gradually with maturation. Weak immunoreactivity was also observed in endothelial cells and fibroblast-like cells in pulpal and periodontal tissues. Howver, no reactivity was seen in ameloblasts. These results suggest the possible involvement of PGI-2 in the regulation of the metabolism of various calcified tissues. Monoclonal antibodies such as isn-1 may become useful markers of the maturation of calcified tissue-forming cells of mesenchymal origin.

US$19.90

PMID: 8442718

DOI: 10.1016/0003-9969(93)90151-b


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Cuadra, M.Bach.; Pollo, C.; Bardera, A.; Cuisenaire, O.; Villemure, J-Guy.; Thiran, J-Philippe., 2004: Atlas-based segmentation of pathological MR brain images using a model of lesion growth. We propose a method for brain atlas deformation in the presence of large space-occupying tumors, based on an a priori model of lesion growth that assumes radial expansion of the lesion from its starting point. Our approach involves three steps. Fi...

Amis, A.A.; Oguz, C.; Bull, A.M.J.; Senavongse, W.; Dejour, D., 2008: The effect of trochleoplasty on patellar stability and kinematics: a biomechanical study in vitro. Objective patellar instability has been correlated with dysplasia of the femoral trochlea. This in vitro study tested the hypothesis that trochleoplasty would increase patellar stability and normalise the kinematics of a knee with a dysplastic tro...

Preller, M.; Holmes, K.C., 2014: The myosin start-of-power stroke state and how actin binding drives the power stroke. We propose that on binding to actin at the start of the power stroke the myosin cross-bridge takes on the rigor configuration at the actin interface. Starting from the prepower stroke state, this can be achieved by a small movement (16° rotation)...

Rahaghi A., 1973: Study of some larger foraminifera of the Qum Formation (central Iran). Twenty-three species identified, one new genus, three new species, Miocene.

Obis, Mb, 1993: Take another look at soyfoods. Vegetarian times: (192) 54-66not

Kloudova, A., 1976: Membrane transport in bacteria. The methods of studying active membrane transport in bacteria are described and its mechanisms are classified. Membrane and periplasmic components of various transport systems were isolated and characterized. Membrane vesicles are frequently used...

Matsuda N.; Komaki M., 1980: Survival curves for spores of clostridium botulinum 62a obtained by the anaerobic pour plate and the anaerobic pouch methods. The survival curves of spores of C. botulinum 62A (ATCC 7948) subjected to isothermal heat treatment were obtained by the anaerobic pour plate and the anaerobic pouch methods. No significant difference was found between the survival curves obtaine...

Cho, D.; Inuzuka, T.; Watanabe, H.; Tsuji, S.; Goto, T.; Kishi, K.; Okamoto, K.; Ito, Y., 1995: A case of consciousness disorder, convulsion, meningeal stimulation, ocular motility disorder and ataxia induced by cyclosporin. Nihon Naika Gakkai Zasshi. Journal of the Japanese Society of Internal Medicine 84(7): 1161-1162

Chaillou, P.; Moussu, P.; Noel, S.F.; Sagan, C.; Pistorius, M.A.; Langlard, J.M.; Patra, P., 1997: Spontaneous dissection of the celiac artery. We describe a case of intestinal angina caused by spontaneous dissection of the celiac artery and thrombosis of the superior mesenteric artery. Spontaneous dissection of a visceral artery is an uncommon occurrence that is usually diagnosed after f...

Sinclair P.; Jacobs J.; Bement W.; Lambrecht R.; Sinclair J.; Goldstein J., 1990: Oxidation of uroporphyrinogen by methylcholanthrene induced cytochrome p 450 essential role of cytochrome p 450 d. Molecular Aspects of Medicine 11(1-2): 115