geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immunohistochemical expression of endothelial markers in left atrial myxomas: A study of six cases


, : Immunohistochemical expression of endothelial markers in left atrial myxomas: A study of six cases. Histopathology (Oxford) 28(2): 147-152

Vascular endothelial cells are antigenically heterogeneous and therefore it has been recommended that a range of immunohistochemical markers is employed to show the presence of cells of endothelial origin in surgical pathology. In this study we applied three monoclonal antibodies--to factor VIII-related antigen, JC70 (CD31), QBend 10 (CD34)--and Ulex europaeus agglutinin type 1 lectin (UEA-1), to six consecutive cases of left atrial myxoma. We found that JC70 and QBend 10 consistently stained myxoma cells in all their different growth patterns contrasting with factor VIII-related antigen expression and UEA-1 binding which were restricted to areas which showed morphological evidence of vascular differentiation. These findings suggest that the constituent cells of atrial myxomas show more widespread endothelial differentiation than has previously been recognized and that differences in immunohistochemical staining may reflect the maturation status of these cells.

US$19.90

PMID: 8834523

DOI: 10.1046/j.1365-2559.1996.271316.x


Other references

Sasaki, I.; Kaisho, T., 2015: Transcriptional control of dendritic cell differentiation. Dendritic cells (DCs) are professional antigen presenting cells involved critically not only in provoking innate immune responses but also in establishing adaptive immune responses. Dendritic cells are heterogenous and divided into several subsets...

Holland, J.C.; Linn, C.E.; DiGiammarino, E.; Nichols, R.; Howell, E.E., 1993: Does R67 dihydrofolate reductase possess a proton donor?. Advances in Experimental Medicine and Biology 338: 493-498

Theiss, W.; Wirtzfeld, A.; Fink, U.; Maubach, P., 1983: The success rate of fibrinolytic therapy in fresh and old thrombosis of the iliac and femoral veins. Since it is still a wide-held belief that fibrinolytic therapy can clear thrombi from deep veins only while they are fresh, we retrospectively analyzed the phlebographic results obtained in 85 patients with thrombosis of the iliac and/or femoral v...

Falholt K.; Dohn K.; Falholt W., 1972: Intra cellular enzyme pattern in human skeletal muscle during hypoxia. Scandinavian Journal of Clinical & Laboratory Investigation Supplement 29(126): 5

Lindberg; Koch; Haug, 1986: Structure, formation, and motion of kinks in increasing-absorption optical bistability. Physical Review. A, General Physics 33(1): 407-415

Lukashov, V.N., 2001: Role of perennial fodder legumes in the fodder production system. Results are discussed of trials held in Kaluga province, Russia, in 1995-2000 to determine the effects on yields, energy costs and soil fertility of growing perennial fodder legumes and legume-grass/cereal mixtures in order to produce high energy...

Silva J.F.C.D.; Valadares Filho S.D.C.; Leao M.I.; Castro A.C.G.; Costa W.P.D., 1991: Effect of monensin and urea on intake ruminal parameters apparent digestibility and nutritional balance in cattle. Sixteen holstein steers eighteen month old, weighing on average 300 kg and rumen fistulated, were used to study the effect of sodium monensin and urea in the ration. They were based on rice straw (49%) and concentrate (51%). A completely randomize...

Marshall, LG., 1978: Glironia venusta. Mammalian Species, 1-3 No. 107

Senel, S., 2016: Oral Mucosa for Delivery of Drugs, Allergens and Vaccines: Where are we Now?. Current Drug Delivery 13(2): 172-174

Marx, W., 1980: A 1. Berliner und Munchener tierarztliche Wochenschrift5, 93(14): 264-266