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Immunohistochemical identification and effects of atrial natriuretic peptide, pancreastatin, leucine-enkephalin, and galanin in the porcine pancreas


, : Immunohistochemical identification and effects of atrial natriuretic peptide, pancreastatin, leucine-enkephalin, and galanin in the porcine pancreas. Peptides (tarrytown). 17(3): 503-509

This study demonstrates the presence and distribution of atrial natriuretic peptide (ANP) pancreastatin (PST), leucine-enkephalin (Leu-ENK), galanin (GAL), and insulin in the pig pancreas. The effects of PST, ANP, Leu-ENK, and GAL on protein and amylase secretion were also investigated to determine their functional role in the control of pancreatic secretion. PST-immunoreactive cells were observed in the islet of Langerhans and in the wall of the ducts. Leu-ENK-immunopositive cells were observed in both the endo- and exocrine pancreas. It is co-localized with insulin in the islet of Langerhans. ANP immunoreactivity was discernible in nerve fibers and cells of the exocrine pancreas. GAL-immunopositive cells were observed in close association with insulin-positive cells in the islets of Langerhans and in the exocrine pancreas. Stimulation of isolated pancreatic segments with either ANP or Leu-ENK resulted in increased protein secretion and amylase output. The Leu-ENK-evoked amylase secretion was antagonized by naloxone. Pancreastatin was effective at all concentrations, but low concentration had more marked secretory effects whereas GAL failed to evoke any significant increases in either protein or amylase secretion. The results of the study have demonstrated a close association of peptidergic fibers with the secretory cells of the pancreas. The nerve fibers can release peptides that in turn can stimulate protein and amylase secretion.

US$19.90

PMID: 8735979

DOI: 10.1016/0196-9781(96)00011-3


Other references

Kosnar Richard A.; Bergman Kosnar Tresa; Tealdi E., 1995: Crystallized gold in Colorado, USA; Part 2, History and production of crystallized gold specimens from the major mines of the Colorado mineral belt from 1859 to 1993. Rivista Mineralogica Italiana 1995(1): 81-95

Raimondi, G.A., 1987: Hemodynamic monitoring in adult respiratory distress syndrome. Medicina 47(4): 416-430

Novello, V.; Gay, G.; Bovio, M., 1981: Studies on the effects of two growth regulators, Ergostim and chlormequat, on grapevines of the cultivar Merlot. Applying 300 p.p.m. Ergostim, a mixture of folcysteine (3-acetyl thiazolidin-4-carboxylic acid), folic acid and hexamethyltetramine, to Merlot/Kober 5BB grapevines (trained as espaliers and double curtains) at early flowering and 10 days later had...

Pierri A., 1980: Treatment of post traumatic coma limitation of antibiotics and cortico steroids. Survival, in a group of 113 patients in coma was markedly improved by very limited prophylactic antibiotic therapy and without steroids. Mortality dropped from 73.7% in the treated patients to 53.6% in those without corticosteroids and antibiotic...

Allen, E.J.; Moerel, M.; Lage-Castellanos, Aín.; De Martino, F.; Formisano, E.; Oxenham, A.J., 2017: Encoding of natural timbre dimensions in human auditory cortex. Timbre, or sound quality, is a crucial but poorly understood dimension of auditory perception that is important in describing speech, music, and environmental sounds. The present study investigates the cortical representation of different timbral...

Tammaa, A.; Aigmüller, T.; Hanzal, E.; Umek, W.; Kropshofer, S.; Lang, P.F.J.; Ralph, G.; Riss, P.; Koelle, D.; Jundt, K.; Tamussino, K.; Bjelic-Radisic, V., 2017: Retropubic versus transobturator tension-free vaginal tape (TVT vs TVT-O): Five-year results of the Austrian randomized trial. To compare outcomes of the retropubic versus the transobturator tension-free vaginal tape (TVT vs TVT-O) at 5 years. A total of 569 women undergoing surgery for primary stress incontinence were randomized to receive a retropubic or a transobturato...

Christensen, T.D.; Jensen, C.; Larsen, T.B.; Maegaard, M.; Christiansen, K.; Sørensen, B., 2010: International Normalized Ratio (INR), coagulation factor activities and calibrated automated thrombin generation - influence of 24 h storage at ambient temperature. International Normalized Ratio (INR) measurements are used to monitor oral anticoagulation therapy with coumarins. Single coagulation factor activities and calibrated automated thrombin (CAT) generation are considered as more advanced methods for...

Norn, S., 1967: Release of histamine from sensitized rat peritoneal cells by specific and unspecific antigens. Peritoneal cell suspensions from rats sensitized with proteins, release about 50% of their histamine content if incubated in vitro with the specific protein (horse serum or egg albumin). Only 3% is released if cells from non-sensitized rats are in...

Sugawara, Y.; Okamoto, Y.; Sawahata, T.; Tanaka, K., 1993: Skin reactivity in guinea pigs sensitized with 2,4-toluene diisocyanate. Skin reactivity in guinea pigs sensitized with 2,4-toluene diisocyanate (TDI) has been examined. For sensitization, guinea pigs were treated daily with a 10% TDI solution in ethyl acetate by intranasal application for 5 consecutive days. Local app...

Farhat-Mchayleh, N.; Sabbagh, J.; Souaid, P., 2008: Multidisciplinary approach to behavior control of children during dental care: clinical study on the effect of learning by imitation. Many techniques of behavioral control of children have been developed to help the good performance of their health treatment. The objective of this study was to test the effect of the "modeling" technique on the pulse of the children dur...