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Immunohistochemical investigation of nasopharyngeal carcinoma using keratin, EMA, laminin, fibronectin, collagen type IV, laminin receptor, and laminin/collagen receptor antibodies


, : Immunohistochemical investigation of nasopharyngeal carcinoma using keratin, EMA, laminin, fibronectin, collagen type IV, laminin receptor, and laminin/collagen receptor antibodies. Acta Medica Nagasakiensia 38(2-4): 182-185

Immunohistochemical investigation was carried out to examine the characteristics of nasopharyngeal carcinoma (NPC) using 12 biopsy cases obtained from southern China. These cases were divided into three groups according to their predominant pattern associated with the cell and the tissue differentiation using the World Health Organization (WHO) classification as follows: (i) 4 cases with squamous cell carcinoma, (ii) 4 cases with differentiated nonkeratinizing carcinoma, (iii) 4 cases with undifferentiated carcinoma. These three types of NPC cases were reacted with keratin and epithelial membrane antigen (EMA). All neoplastic tissues were stained with keratin stronger than EMA. Squamous cell carcinoma and differentiated non-keratinizing carcinoma cases were diffusely stained strongly positive by immunoperoxidase for keratin. On the other hand, most of undifferentiated carcinoma cases were weakly or negatively reacted with keratin immunohistochemistry, and a part of tumor cytoplasms were stained strongly positive by keratin immunoreaction. For EMA immunoperoxidase method, squamous cell carcinoma cases were diffusely positive and most of differentiated non-keratinizing carcinoma and undifferentiated carcinoma cases were partly positive. However, none of NPC cases reacted with immunoreactivity for laminin 200, laminin 400, fibronectin, collagen, laminin receptor, and laminin/collagen receptor. Therefore, immunohistochemical characteristics of NPC showed epithelial cell origin, arising from squamous cells in nasopharynx.

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Other references

Tesfayohannes, T., 1989: Prevalence of body lice in elementary school students in three Ethiopian towns at different altitudes. A survey of body lice in three different altitudinal zones of Ethiopia was conducted. The survey population consisted of primary school children of both sexes ranging in age from 6-25 years. The areas of study were Gambela, Kemise and Debre-Berhan...

Banerjee, N.; Mazumdar, S.K.; Bose, S.K., 1959: Some preliminary studies on the evaluation of mycobacillin for therapeutic use. Bull Calcutta Sch Trop Med 7(2): 35-36

Anderson P.R.; Oakeshott J.G., 1984: Parallel geographical patterns of allozyme variation in 2 sibling drosophila spp. Nature (London) 308(5961): 729-731

Appel, A.G.; Moar, W.J.; Tanley, M.J., 1999: Water loss and mortality of adult cowpea weevils (Coleoptera: Bruchidae) exposed to desiccants and desiccating environments. Water relations and desiccation tolerance of adult cowpea weevils, Callosobruchus maculatus (F.), were examined in response to exposure to desiccants and desiccating environments. Cuticular permeability was similar for both sexes (approximately eq...

Jones T.R.; Plakke R.K., 1981: The histology and histochemistry of the peri anal scent gland of the reproductively quiescent black tailed prairie dog cynomys ludovicianus. The black-tailed prairie dog (C. ludovicianus) has a trilobate perianal scent gland located between the internal and external anal sphincter muscles. Two of the lobes lie ventro-lateral to the rectal canal and the remaining lobe lies ventral to th...

Verstraete, M.; Caracas, R., 2009: The effect of FeSi alloys on the seismology and transport properties of the lowermost mantle and the outer core. Eos, Transactions, American Geophysical Union 90.52, SUPPL

Marshall, N.A.; Chapman, M.D.; Saxon, A., 1986: Species-specific allergens from the salivary glands of Triatominae (Heteroptera:Reduviidae). We investigated allergenic cross-reactivity among species of the blood-feeding insects of the subfamily Triatominae. By skin testing, patients allergic to either Triatoma protracta or T. rubida gave positive responses only to the respective saliva...

Johnson, K.R.; Lewis, J.E.; Li, D.; Wahl, J.; Soler, A.P.; Knudsen, K.A.; Wheelock, M.J., 1993: P- and E-cadherin are in separate complexes in cells expressing both cadherins. E- and P-cadherin are members of a family of calcium-dependent, cell surface glycoproteins involved in cell-cell adhesion. Extracellularly, the transmembrane cadherins self-associate, while intracellularly, they interact with the actin-based cytos...

Hall, Fr, 1980: Opportunities for increased efficiency of spraying high density orchards. Compact fruit tree 13(13): 9-13

Meyer W.J.IIi; Furlanetto R.W.; Matustik M.C., 1982: Human chorionic gonadotropin stimulation in infants with micro phallus and hypo pituitarism. Journal of Andrology 3(1): 13-14