geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Immunohistochemical localization and distribution of cholecystokinin octapeptide in porcine, rat and guinea pig intestinal tract


, : Immunohistochemical localization and distribution of cholecystokinin octapeptide in porcine, rat and guinea pig intestinal tract. Acta Zoologica Sinica 41(2): 181-184

Cholecystokinin (CCK), a peptide with multiple molecular forms and physiological functions, is widely distributed in both the nervous system and the endocrine cells of digestive tract. In this study, the localization and distribution of cholecystokinin octapeptide (CCK-8) in the porcine, rat and guinea pig intestinal tract were investigated by ABC immunohistochemical technique, and the possible coexistence of CCK-8 with serotonin was also observed by using adjacent section double immunolabelling method. It was found that the CCK-8 immunoreactive (CCK-8-IR) cells were maidy localized in the lower parts of intestinal glands, while only a few could be observed on the epithelium of villi. In the aspect of segmental distribution. the CCK-8-IR cells could be seen in the mucosa of the whole intestinal tract from duodenum to colon in pig, while in rat and guinea pig, the CCK-8-IR cells were only seen in the mucosa from duodenum to ileum. But, in the aspect of quantity, the density of CCK-8-IR cells showed the highest number only in duodenum. Nearby the adjacent sections of the duodenum, the results obtained by double immunolabelling method proved the coexistence of CCK-8 and serotonin in the intestinal tracts of all three animals.

US$29.90


Other references

Thurnham, D.I., 1994: Carotenoids: functions and fallacies. In this review, the author discusses some of the functions of carotenoids, their structure, and their distribution with in tissues. The role of beta-carotene in cardiovascular disease and cancer is addressed along with the subject of carotenoids a...

Xu, T.; Wang, X.; Hou, S., 2002: Effect of lower androgen levels on arteriosclerosis. To analyse the effect of lower androgen levels on risk factors for arteriosclerosis of men. In 30 cases of primary prostate carcinoma (stage A), serum levels of testosterone (T), free testosterone (FT), dehydroepiandrosterone (DHEA), sex hormone-b...

Adams, E.B.; Wright, R.; Berman, E.; Laurence, D.R., 1959: Treatment of tetanus with chlorpromazine and barbiturates. Lancet 1(7076): 755-757

Oakberg, E.F., 1978: Differential spermatogonial stem cell survival and mutation frequency. One group of adult C3H .times. 101 hybrid male mice was given 3 injections of 12.5 .mu.Ci microcuries of [3H]thymidine at 9-h intervals and irradiated 24 h after the last injection with X-ray doses of 100, 300, 500, 600, 1000 R or the first fracti...

Peirce, J.C.; Miller, A.F.; Mayer, L.S.; Westly, J., 1997: A randomized clinical trial of a group empowerment program for somatizing patients Six months follow-up results. Jgim 12(Suppl 1): 115

Grimm, S.; Stinchcomb, D.T.; Mcswiggen, J.; Sullivan, S.; Draper, K.G., 2000: Ribozyme treatment of diseases or conditions related to levels of intercellular adhesion molecule-1. Enzymatic RNA molecules which cleave ICAM-1 mRNA.

Schrier, S.A.; Bodurtha, J.N.; Burton, B.; Chudley, A.E.; Chiong, M.Anne.D.; D'avanzo, M.Gabriella.; Lynch, S.Ann.; Musio, A.; Nyazov, D.M.; Sanchez-Lara, P.A.; Shalev, S.A.; Deardorff, M.A., 2012: The Coffin-Siris syndrome: a proposed diagnostic approach and assessment of 15 overlapping cases. Coffin-Siris syndrome (CSS) is a rare, clinically heterogeneous disorder often considered in the setting of cognitive/developmental delay and 5th finger/nail hypoplasia. Due to the clinical variability of facial and other features, this diagnosis...

Chen, X.; Köllner, T.G.; Jia, Q.; Norris, A.; Santhanam, B.; Rabe, P.; Dickschat, J.S.; Shaulsky, G.; Gershenzon, J.; Chen, F., 2016: Terpene synthase genes in eukaryotes beyond plants and fungi: Occurrence in social amoebae. NlmCategory="UNASSIGNED">Terpenes are structurally diverse natural products involved in many ecological interactions. The pivotal enzymes for terpene biosynthesis, terpene synthases (TPSs), had been described only in plants and fungi...

Mccaffree, J.D., 1971: An analysis of records on New York State dairy farms. An analysis of 1, 277 Farm Business Records (FBR) and 704 Dairy Herd Improvement Records (DHI) was conducted to determine which input variables collected by these systems would be most useful to determine optimum output in terms of milk output and...

Shimizu, M., 1973: Erythrocyte metabolism and ceruloplasmin. Japanese Journal of Clinical Hematology 14(4): 502-506