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Lamellar keratoplasty in the management of inflammatory corneal ulceration and perforation


, : Lamellar keratoplasty in the management of inflammatory corneal ulceration and perforation. Eye 8: 22-28

Corneal ulceration and perforation may occur in the course of several systemic and ocular inflammatory conditions. These serious complications may respond to systemic immunosuppression and conjunctival surgery, but tectonic keratoplasty is sometimes required. We report on 10 cases of corneal ulceration (of which 8 suffered perforation) in patients with rheumatoid arthritis, Stevens-Johnson syndrome and Mooren's ulceration which were treated by lamellar keratoplasty. Our microsurgical technique for lamellar keratoplasty benefited from the use of viscoelastic agents, cyanoacrylate adhesive and an adjustable stepped diamond knife. These recent advances have made this procedure as easy to perform as a penetrating keratoplasty. Lamellar keratoplasty virtually eliminates the risk of graft rejection and reduces the risk of perforation in the event of a subsequent exacerbation of the melting process. Surgery preserved the globe in all 10 cases, and the pre-operative visual acuity was maintained or improved in all but 1 case. Six patients achieved a visual acuity of 6/60 or better. Concomitant systemic immunosuppression was used in 6 cases and a subsequent penetrating keratoplasty performed in 3 cases. Lamellar keratoplasty provides a valuable method of preserving the integrity of the globe and maintaining useful vision in these difficult cases.

US$19.90

PMID: 8013714

DOI: 10.1038/eye.1994.4


Other references

Siebenenrock, K., 1937: The organs of white rats on deficient diets. 2. The effects of various dietaries and supplements on the histological appearance of the organs of white rats are described. In the absence from the diet of the " yeastcereal factor, " parenchymatous degeneration was noted in the liver and...

Chung H.M.; Sackett W.M., 1976: Carbon isotope studies on organic metamorphism. Abstracts with Programs - Geological Society of America 8(1): 13-14

Gavelin Axel, 1943: Minnesord oever C. F. Kolderup. Brief obituary notice of C. F. Kolderup (1869-1942), Norwegian geologist who was director of the Bergens Museum.

Eskandari, M.Reza.; Rahmati, M.; Khajeamiri, A.Reza.; Kobarfard, F.; Noubarani, M.; Heidari, H., 2014: A new approach on methamphetamine-induced hepatotoxicity: involvement of mitochondrial dysfunction. 1.  Methamphetamine (METH) is a highly addictive stimulant that is among the most widely abused illicit drugs. Clinical evidence has shown that the liver is a target of METH toxicity. The exact cellular and molecular mechanisms involved in METH-...

Charpy R., 1968: French fishery production. Bulletin Technique d'Information des Ingenieurs des Services Agricoles (228): 345-354

Khan, A.R.; Brubaker, R.F., 1993: Aqueous humor flow and flare in patients with myotonic dystrophy. Purpose. Myotonic dystrophy is an autosomal dominant form of muscular dystrophy associated with a mutation that affects a gene on chromosome 19. Extremely low intraocular pressure is one of a constellation of clinical signs that sometimes accompan...

Zoz, I.G., 1963: Bowiea volubilis Harvey, a medicinal plant.. Bowiea volubilis (Liliaceae, Bowieae) is a South African plant, the bulbs of which are used medicinally by the local population. Results of earlier studies on the biological activity of the bulbs are quoted from the literature, and a table is give...

Yokozawa, T.; Fujioka, K.; Oura, H.; Tanaka, T.; Nonaka, G.I.; Nishioka, I., 1995: Decrease in uraemic toxins, a newly found beneficial effect of Ephedrae Herba. The effects of Ephedra distachya on the serum concentrations of urea nitrogen, creatinine, methylguanidine and guanidinosuccinic acid, which accumulate in the blood in parallel with the progress of renal failure after adenine administration, were...

Edgerton, M.; Cline, M.G.; Rehm, M.M., 1975: The lack of effect of cyclic adenosine 3':5'-monophosphate on Avena coleoptile growth. Coleoptile segments of oats cv. Victory were treated with 0.1 or 2mM cAMP with or without 2.5mM glucose or with 0.1mM dibutyryl-cAMP or 2mM c-guanosine monophosphate for varying times. The growth of the segments was measured and it was found that...

Chen, Y.; Bi, J., 2007: Biogeography and hotspots of amphibian species of China: Implications to reserve selection and conservation. Studies on species' biogeography, biodiversity are of remarkable significance in biogeographic regionalization and systematic conservation. In this article, we employed various numerical approaches to investigate distributions of amphibian s...