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Multivessel coronary thrombosis treated with abciximab (ReoPro) in a patient with essential thrombocythemia


, : Multivessel coronary thrombosis treated with abciximab (ReoPro) in a patient with essential thrombocythemia. Clinical Cardiology 21(2): 134-138

A 50-year-old man was admitted with acute inferior and anterior myocardial infarction. The patient was diagnosed with essential thrombocythemia (ET) based on the findings of marked thrombocytosis of 1,113 x 10(3)/mm3, splenomegaly, and numerous clumping megakaryocytes on bone marrow biopsy. Emergent coronary angiography revealed extensive multivessel thrombosis involving the left main coronary artery and completely occluding the proximal right coronary artery. In addition to standard therapy with aspirin, heparin, and primary angioplasty of the right coronary artery, the patient received additional antiplatelet therapy with ticlopidine, hydroxyurea, and the platelet glycoprotein IIb/IIIa receptor-inhibiting monoclonal antibody drug abciximab (ReoPro). Serial coronary angiograms 1 and 5 days following the infarction showed progressive thrombus resolution. The pathophysiologic mechanisms and therapeutic challenges of ET-associated coronary thrombosis are discussed in this report.

US$19.90

PMID: 9491958

DOI: 10.1002/clc.4960210218


Other references

Silver Eli A.; Barnard William D., 1971: Pleistocene tectonics of the Washington continental slope. Abstracts with Programs Geological Society of America: Pages 193. 1971.

Denton, C.P.; Nihtyanova, S.I., 2007: Therapy of pulmonary arterial hypertension in systemic sclerosis: an update. Pulmonary arterial hypertension (PAH) affects 10% to 15% of patients with systemic sclerosis and is a major cause for disease-related morbidity and mortality. Over the past decade, significant progress has been made in the understanding of the pat...

Tsuchiya, N.; Slezak, J.M.; Lieber, M.M.; Bergstralh, E.J.; Jenkins, R.B., 2002: Clinical significance of alterations of chromosome 8 detected by fluorescence in situ hybridization analysis in pathologic organ-confined prostate cancer. Loss of 8p22 and gain of 8q24 are known to be common chromosomal alterations in prostate cancer. We have previously demonstrated that concurrent 8q24 overrepresentation and 8p22 loss were associated with a poor prognosis in patients with high-grad...

Gabel, J.C.; Gallagher, H.; Garewal, D.; Drake, R.E., 1993: Analysis of lung lymph flow by equating passive flow and lymphatic pump function relationships. FASEB Journal 7(3-4): A235

Gay Prieto, J., 1955: Pseudopelade of Brocq: its relationship to some forms of cicatricial alopecias and to lichen planus. Journal of Investigative Dermatology 24(3): 323-335

Esau, K.; Charvat, I.D., 1975: An ultrastructural study of acid phosphatase localization in cells of Phaseolus vulgaris phloem by the use of the azo dye method. The localization of acid phosphatase was studied in the sieve elements and companion cells in the phloem tissue of the bean, Phaseolus vulgaris L. The various organelles in the two kinds of cell showed fine granules of the azo dye as the final rea...

Lyla, PS.; Panchatcharam, K.; Ajmal Khan, S., 1999: Breeding biology of the stomatopod Harpiosquilla melanoura (Crustacea: Stomatopoda) occurring in Parangipettai waters, southeast coast of India. The present study on breeding biology of Harpiosquilla melanoura Manning occurring in Parangipettai waters covers size at first maturity, sex ratio, fecundity and annual reproductive cycle. The minimum size at first maturity was found to be 142 mm...

Sekiyama, S.; Mogi, K.; Inawashiro, M.; Kmoribayashi, N.; Oashi, Y., 1973: Postoperative management of radical neck dissection with continuous suction drainage. Nihon Koku Geka Gakkai Zasshi 19(3): 276-282

Bellamy, D., 2000: Progress in the management of COPD. Practitioner 244(1606): 24, 27-28, 30

Felton, E.A.; Niven, C.F., Jr., 1953: The identity of. A full taxonomic study of the characteristics of Leuconostoc citrovorum strain 8081 suggested that the organism was a pediococcus. The citrovorum factor requirement of 6 strains of pediococci was investigated and all responded to leucovorin and to...