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New derivatives of imidazole as potential anticancer agents


, : New derivatives of imidazole as potential anticancer agents. Farmaco (lausanne). 53(5): 342-345, 30

A series of monocyclic amidinohydrazones 2a-h was prepared from the reaction of N-(4,5-dihydro-1H-imidazol-2-yl)-N-(2-hydroxyethyl)hydrazine hydroiodide 1 with various aromatic aldehydes. Some of them were subjected to an esterification with acetic anhydride to give 2a-d. Compounds 2a,c,d,e,f,h and 3c were tested for their anticancer and anti-HIV activity.

US$19.90

PMID: 9679284

DOI: 10.1016/s0014-827x(98)00031-7


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