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New oligosaccharidic crown ethers as potential drug-targetting vectors: Synthesis and biological evaluation


, : New oligosaccharidic crown ethers as potential drug-targetting vectors: Synthesis and biological evaluation. Bioorganic and Medicinal Chemistry Letters 4(9): 1123-1126

Two potential carriers (compounds 4 and 6), incorporating one galactose residue linked to a 18-6 crown ether as complexing tool, were synthesized for the first time using the trichloracetimidate method and evaluated for their in vitro specific recognition of a cell wall galactose-specific yeast lectin (KbCWL).

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