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Oral hairy leukoplakia in a patient with multiple myeloma

, : Oral hairy leukoplakia in a patient with multiple myeloma. Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics. 82(4): 408-410

The first case of oral hairy leukoplakia in an HIV-negative patient with multiple myeloma is reported. The patient is a 56-year old man who has had monoclonal gammopathy of undetermined significance since 1986 and has been treated for a symptomatic multiple myeloma since 1 993. The clinical and histopathologic findings are typical for oral hairy leukoplakia, and Epstein-Barr virus was demonstrated with polymerase chain reaction technique. Although a relatively large number of cases of oral hairy leukoplakia has been reported in HIV-negative patients, both immunocompromised and immunocompetent, only a few of these patients have had a malignant hematologic disease.


PMID: 8899778

DOI: 10.1016/s1079-2104(96)80305-2

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