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Postpartum blood pressure and insulin sensitivity in African-American women with recent preeclampsia

, : Postpartum blood pressure and insulin sensitivity in African-American women with recent preeclampsia. American Journal of Hypertension 7(10 Pt 1): 933-936

Pregnancy-induced hypertension and preeclampsia are relatively common in nulliparous, inner-city, African-American, pregnant women and contribute to considerable maternal, fetal, and neonatal morbidity and mortality in that population. Recently, insulin resistance has been related to the development of hypertension in young African-Americans and hyperinsulinemia and elevated insulin-to-glucose ratios, suggesting insulin resistance, have been demonstrated in women with preeclampsia. To investigate whether insulin resistance existed postpartum and, therefore, independently of the pregnant state, the hyperinsulinemic, euglycemic technique was used 3 to 6 months postpartum to assess insulin sensitivity in 10 young, black, primiparous, inner-city women with recent preeclampsia and seven age-, weight- and body-mass-index-matched black women with healthy pregnancies. The age, weight, body-mass index, waist-to-hip ratio, the duration since parturition, and fasting plasma glucose and insulin were similar in the preeclamptic and control groups. During the clamp procedure, the insulin levels and mean diastolic blood pressure and mean arterial pressure were also similar for both groups; however, the mean systolic blood pressure of the preeclamptic group (123 +/- 3 mm Hg) was higher than that of the control group (114 +/- 2 mm Hg) (P < .05). Insulin-stimulated glucose disposal was not different between the preeclamptic (5.6 +/- 0.3 mg/kg/min) and control groups (5.7 +/- 0.7 mg/kg/min). This suggests that the elevation in postpartum systolic blood pressure may reflect a persistent abnormality of blood pressure homeostasis which is not associated with insulin resistance.


PMID: 7826558

DOI: 10.1016/0895-7061(94)P1717-E

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Niu, H-yan.; Zeng, Q-fu.; Li, X.; Chu, L.; Hu, Y-bin.; Wang, J-sheng., 2004: The role of Egr-1 and NF-kappaB in the pathogenesis of silicosis: an in-vitro study. To study the correlation between the expression of Egr-1 and NF-kappaB and the up-regulation of TNF-alpha and TGF-beta1 in macrophages after stimulation by silica in-vitro. Macrophages were treated with antibodies against Egr-1 and NF-kappaB and a...

Schneider, C., A.; Voth, E.; Moka, D.; Baer, F., M.; Melin, J.; Bol, A.; Wagner, R.; Schicha, H.; Erdmann, E.; Sechtem, U., 1999: Improvement of myocardial blood flow to ischemic regions by angiotensin-converting enzyme inhibition with quinaprilat IV: A study using (15O) water dobutamine stress positron emission tomography. OBJECTIVES: This study was designed to analyze the effects of acute angiotensin-converting enzyme (ACE) inhibition on myocardial blood flow (MBF) in control and ischemic regions. BACKGROUND: Although animal studies indicate an improvement of MBF t...

Gupta, S., 1987: Gross morphological alterations in gonads of Channa punctatus (Bloch) chronically exposed to vegetable oil factory effluent. Unknown

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