+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Primary cutaneous T-cell lymphoma with an angiocentric growth pattern: Association with Epstein-Barr virus

, : Primary cutaneous T-cell lymphoma with an angiocentric growth pattern: Association with Epstein-Barr virus. British Journal of Dermatology 135(4): 638-643

We report a case of primary cutaneous T-cell lymphoma with an angiocentric growth pattern. The lesions had been confined for about 2.5 years to the skin, but there had been a gradual progression of the disease both clinically and histologically. We assessed the neoplastic clonality and the presence of Epstein-Barr (EB) virus genome in this case using immunohistochemistry, Southern blot analysis and RNA in situ hybridization. Clonal proliferation of a CD4+ alpha-beta T-cell phenotype was demonstrated. In addition, the clonal population harboured the EB virus genome, which suggested that the virus was involved in the pathogenesis of the disease, The patient has remained in remission for 10 months, and has received treatment with cyclophosphamide and prednisone.


PMID: 8915164

DOI: 10.1046/j.1365-2133.1996.d01-1058.x

Other references

Goldstone, A.P.; Miras, A.D.; Scholtz, S.; Jackson, S.; Neff, K.J.; Pénicaud, L.; Geoghegan, J.; Chhina, N.; Durighel, G.; Bell, J.D.; Meillon, S.; le Roux, C.W., 2016: Link Between Increased Satiety Gut Hormones and Reduced Food Reward After Gastric Bypass Surgery for Obesity. Roux-en-Y gastric bypass (RYGB) surgery is an effective long-term intervention for weight loss maintenance, reducing appetite, and also food reward, via unclear mechanisms. To investigate the role of elevated satiety gut hormones after RYGB, we ex...

Binenfeld, Z., 1957: Water and food in modern warfare; problems of contamination and decontamination. Vojnosanitetski Pregled 14(12): 785-791

Aylsworth, Jean D., 1995: Keep the hail from falling. American Fruit Grower 115: 16

Bisaria, V.S.; Mishra, S., 1989: Regulatory aspects of cellulase biosynthesis and secretion. The cellulase enzyme system consists of cellobiohydrolase, endoglucanase, and beta-glucosidase and has been extensively studied with respect to its biosynthesis, properties, mode of action, application, and, most recently, secretion mechanisms. A...

Premachandran D., 1981: The biochemical mechanism of resistance in tomato against the root knot nematode meloidogyne incognita. Indian Journal Of Nematology: 108

Ahmad, S.; Shen, F.; Pagel, M.; Goodman, W., 1980: Accelerated creatinine metabolism and elevated CPK with androgen therapy. Proceedings of the Clinical Dialysis and Transplant Forum 10: 174-176

Anonymous, 1954: INCREASE sought in sight-testing fee. British Medical Journal 2(Suppl 2585): 88-88

Siderelis, C.; Moore, R.; Lee JuHee, 2000: Incorporating users' perceptions of site quality in a recreation travel cost model. The travel cost method is used to analyse the recreation demand for trails in North Carolina, USA. Incorporated in the demand model are users' perceptions of trail quality and their stated number of annual trips. Trail demand is specified wit...

Guerin J.; Dautheribes M.; Boulard G., 1987: Cerebral arterial spasm pathophysiology in subarachnoid hemorrhage. Cerebral artery spasm is the more frequent complication in ruptured intracranial aneurysms; furthermore, it is important for prognosis and surgical procedures. Some anatomical features about cerebral vessels and their nerves have to be taken in ac...

Ishida T., 1981: Pliocene and quaternary history of the northern part of sendai lowland area japan a study of structural and geomorphic development. Saito Ho-On Kai Museum of Natural History Research Bulletin (49): 20-36