+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Recombinant human serum amyloid A (apoSAAp) binds cholesterol and modulates cholesterol flux

, : Recombinant human serum amyloid A (apoSAAp) binds cholesterol and modulates cholesterol flux. Journal of Lipid Research 36(1): 37-46

During acute inflammation, the serum amyloid A (apoSAA) proteins apoSAA-1 and apoSAA-2 are transiently associated with high density lipoproteins (HDL) in concentrations of as much as 1000-fold more than their concentrations during homeostasis; however, their effect on HDL function is unclear. Recombinant apoSAAP-p, a hybrid of the closely related human apoSAA-1, and apoSAA-2 isoforms, was found to exhibit a high affinity for cholesterol.


PMID: 7706946

Other references

Phillips, A.O.; Thomas, D.M.; Coles, G.A., 1993: Acute renal failure associated with non-fulminant hepatitis A. A 49-year-old man developed acute renal failure as a complication of non-fulminant hepatitis A. This is a rare association of uncertain etiology.

Andrews, B.F., 1970: Amniotic fluid studies to determine maturity. Pediatric Clinics of North America 17(1): 49-67

Mahoney, J.L., 2011: Adolescent summer care arrangements and risk for obesity the following school year. This longitudinal study identified common summer care arrangements for adolescents and examined whether those arrangements predicted risk for obesity (Body Mass Index (BMI) ≥ 85th percentile for age and gender) the following school year. Partici...

Stratton, R.; Wilson, D.P.; Endres, R.K.; Goldstein, D.E., 1987: Improved glycemic control after supervised 8-wk exercise program in insulin-dependent diabetic adolescents. Eight insulin-dependent adolescents (4 boys, 4 girls) participated in an 8-wk program of supervised exercise, and 8 matched controls were encouraged to exercise on their own without supervision. All 16 subjects were asked to follow a standard ADA...

Bos, J.V.n den; Baltensweiler, W., 1977: Oviposition efficiency of the grey larch bud moth (Zeiraphera diniana) on different substrates and its relevance to the population dynamics of the moth. Studies in Switzerland showed that females of Zeiraphera diniana (Gn.) laid significantly more eggs on larch branches covered with naturally occurring Parmelia lichens than on branches without them. The numbers of eggs deposited and the behaviour...

Cai, L.; Meng, L-Jian., 2013: Hybrid pixel-waveform CdTe/CZT detector for use in an ultrahigh resolution MRI compatible SPECT system. In this paper, we will present a new small pixel CdTe/CZT detector for sub-500 μm resolution SPECT imaging application inside MR scanner based on a recently developed hybrid pixel-waveform (HPWF) readout circuitry. The HPWF readout system consist...

Baltassat, F.; Darbour, N.; Ferry, S., 1985: Studies on the purine content of caffeine drugs. II. Guarana, Paullinia sorbilis Mart. Methylxanthines in the seeds were investigated by HPLC. Large amounts of caffeine (3.69 to 4.79%) were found. Theobromine occurred in small quantities (0.02 to 0.06%), as did theophylline (up to 0.25%) in some samples. [For part I see Horticultura...

Campbell, C.A.; Biederbeck, V.O., 1982: Changes in mineral N and numbers of bacteria and actinomycetes during two years under wheat-fallow in southwestern Saskatchewan. The aim of this study was to identify, in situ, some of the microbial responses to environmental conditions previously noted in experiments in the laboratory and field. Soil samples were taken from a Brown Chernozem under a wheat-fallow rotation a...

Skare, S.; Hanssen, K.F.; Norman, N., 1986: Plasma somatostatin is elevated in primary hypothyroidism compared with hyperthyroidism. Increased pancreatic somatostatin (somatotrophin release inhibiting factor (SRIF)) has been found in hypothyroid rats. Therefore, we wanted to investigate plasma SRIF in patients with hypo- and hyperthyroidism. Two groups of patients, 7 cases with...

D.S.ntis, A.; Pagni, C.A., 1976: Prognostic value of early convulsive seizures in traumatic coma. Rivista di Neurologia 46(5): 400-406