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Regulation and role of intrapituitary IL-6 production by folliculostellate cells

, : Regulation and role of intrapituitary IL-6 production by folliculostellate cells. Domestic Animal Endocrinology 15(5): 353-362, Sept

Interleukin-6, mainly produced by monocytes and macrophages is known to influence the secretion of anterior pituitary hormones and is, therefore, considered to play an important role in the interaction between the immune system and the endocrine system. However, IL-6 represents not only a lymphocyte message but is also produced within the anterior pituitary. Folliculostellate (FS) cells have been identified as the source of the intrapituitary IL-6 production in the normal pituitary, whereas in pituitary adenomas IL-6 is produced by the tumor cells themselves. The present review summarizes the knowledge about the regulation of the intrapituitary IL-6 synthesis and release in FS cells. Moreover, the possible roles of the intrinsic IL-6 production for function and growth of normal and adenomatous endocrine pituitary cells are discussed.


PMID: 9785039

DOI: 10.1016/s0739-7240(98)00027-7

Other references

Huang, Z-Feng.; Viñals, J., 2006: Orientation selection in lamellar phases by oscillatory shears. In order to address the selection mechanism that is responsible for the unique lamellar orientation observed in block copolymers under oscillatory shears, we use a constitutive law for the dissipative part of the stress tensor that respects the un...

Francisco Zamudio; Russ Wolfinger; Brian Stanton; Fernando Guerra, 2008: The use of linear mixed model theory for the genetic analysis of repeated measures from clonal tests of forest trees. I. A focus on spatially repeated data. The paper reviews the linear mixed models (LMM) methodology that is suitable for the statistical and genetic analyses of spatially repeated measures collected from clonal progeny tests. For example, we consider a poplar clonal trial where progenie...

Cancela D.F.nseca, J.P.; Poinsot, N.; Vannier, G., 1967: A comparative study of microarthropods in soil samples of various sizes. Numbers of individuals and species of Oribatei and Isotomidae were compared in soil samples varying in surface area, depth and volume. A sample size of 10 X 10 X 2.5 cm (250 cm 3) is recommended for the ecological study of Oribatei. Distribution o...

Bianchi, P.G.; Manicardi, G.C.; Urner, F.; Campana, A.; Sakkas, D., 1996: Chromatin packaging and morphology in ejaculated human spermatozoa: evidence of hidden anomalies in normal spermatozoa. This study aimed to investigate the association between anomalies in sperm chromatin packaging, morphology and fertilization in patients undergoing routine in-vitro fertilization (IVF) or subzonal insemination (SUZI). Sperm chromatin packaging was...

Hill, J.B.; Cooper, W.M., 1968: Thrombotic thrombocytopenic purpura. Treatment with corticosteroids and splenectomy. Archives of Internal Medicine 122(4): 353-356

Boot, Cécile.R.L.; Hogg-Johnson, S.; Bültmann, U.; Amick, B.C.; van der Beek, A.J., 2015: Differences in predictors for return to work following musculoskeletal injury between workers with and without somatic comorbidities. In workers with musculoskeletal injuries, comorbidity is associated with worse return to work (RTW) outcomes. In the context of RTW, it is unclear whether associations between predictors and RTW are similar or different for workers with and withou...

Borovyĭ, E.M.; Bas, V.M.; Nesterenko, L.N.; Pshenichnyĭ, M.A.; Syvyĭ, N.Iu., 1974: Intestinal obstruction caused by Treitz's hernia. Klinicheskaia Khirurgiia 0(8): 64-64

Hershey, C.D., 1949: Experience with lumbar sympathectomy in vascular diseases of the lower extemity. West Virginia Medical Journal 45(3): 56-62

Kojima M.; Ohnishi M.; Ito S.; Fujino Y., 1989: Characterization of acylmonoglycosylsterol monoglycosylsterol diglycosylsterol triglycosylsterol and tetraglycosylsterol and saponin in adzuki bean vigna angularis seeds. Five sterylglycosides (acylmono-, mono-, di, tri- and tetraglycosylsterol) and a saponin were isolated from Adzuki beans and characterized. In the glycosylsterols, the principal component sterols were sitosterol and stigmasterol; the major sugar c...

Smirnov, A.V.; Burlakova, E.V.; Kol's, O.R.; Sverdlova, E.A.; Fedorov, G.E., 1972: Changes in crab nerve fiber mitochondria during block of conduction caused by different agents. Doklady Akademii Nauk SSSR 203(1): 214-215