geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Relative occurrence of flow limitation and snoring during continuous positive airway pressure titration


, : Relative occurrence of flow limitation and snoring during continuous positive airway pressure titration. Chest 114(3): 685-690

Objectives: To examine the relative temporal appearance of flow limitation and snoring during continuous positive airway pressure (CPAP) titration, compare their sensitivity as indicators of airway obstruction, and assess their relative utility as feedback variables for automatic titration of CPAP. Design: Retrospective review of data. Setting: University teaching hospital. Patients: Fifty-three patients diagnosed as having obstructive sleep apnea or upper airway resistance syndrome undergoing CPAP titration. Measurements and results: We used a prototype automatic CPAF device that adjusts pressure in response to apnea, snoring, and/or flow limitation. The present study takes advantage of the frequent automatic decreases in pressure from a therapeutic level, as well as any technician initiated decreases in pressure. We tabulated, for each pressure decrease of >0.4 cm H2O, the occurrences of snoring alone, flow limitation alone, or simultaneous appearance of both. Of 2,177 automatic pressure decreases, 64% resulted in flow limitation alone, 8% in snoring alone, and 22% in the simultaneous occurrence of both. Overall, 86% of decreases resulted in flow limitation alone or were simultaneous with snoring, whereas 30% of decreases resulted in snoring alone or were simultaneous with flow limitation. In 10 of 35 patients, snoring alone occurred in > 10% of the pressure decreases. In all but 5 of 133 manual pressure decreases, flow limitation developed at or above the pressure at which snoring developed. Conclusions: While detection of snoring occasionally provided additional information, overall flow limitation was the earliest indicator of obstruction during decreases in CPAP.

US$29.90

PMID: 9743151


Other references

Riese W.C.; Franks S.G.; Fehn Udo; Moran Jean E., 1999: Fruitland Formation waters, San Juan Basin, Colorado, and their relevance to understanding Fruitland coalbed methane reservoirs. Published descriptions of reservoir dynamics for coalbed methane reservoirs of the Cretaceous Fruitland Formation of the San Juan Basin, New Mexico and Colorado, USA, hypothesize the importance of present day groundwater recharge to maintain a sta...

Biddison, J.H.; Dembo, D.H.; Spalt, H.; Hayes, M.G.; LeDoux, C.W., 1979: Familial occurrence of mitral valve prolapse in X-linked muscular dystrophy. A high incidence of mitral valve prolapse (MVP) has been reported in patients with X-linked Duchenne muscular dystrophy. In our study MVP was present in six of 22 Duchenne dystrophy cases (27%) followed in the Maryland General Hospital Muscular Dy...

Smith Douglas M.J.; Albinson Tawn; Sawkins Frederick J., 1982: Geologic and fluid inclusion studies of the Tayoltita silver-gold vein deposit, Durango, Mexico. Economic Geology and the Bulletin of the Society of Economic Geologists: , Pages 1120-1145. 1982.

Rahman, S.; Akib, S.; Khan, M.T.R.; Shirazi, S.M., 2014: Experimental study on tsunami risk reduction on coastal building fronted by sea wall. This experimental study was conducted to idealize the efficacy of sea wall in controlling the tsunami forces on onshore structures. Different types of sea walls were placed in front of the building model. The tsunami forces and the wave heights we...

Yi, I.; Stephan, F.K., 1998: The effects of food deprivation, nutritive and non-nutritive feeding and wheel running on gastric stress ulcers in rats. Feeding and housing conditions that induce gastric lesions were investigated. Rats were housed in activity wheels or in hanging cages and exposed to food deprivation, ad lib cellulose or 6 g of cellulose per day for 5 days. Food-deprived rats in b...

Bergman, E.; Smith, J.Gustav.; Wieloch, M.; Braun, O.Ö.; Svensson, P.; van der Pals, J., 2014: Dabigatran in clinical practice--one-year experience at Skåne University Hospital. Thrombosis Research 132(2): 316-317

Lemas, M.V.; Takeyasu, K.; Fambrough, D.M., 1992: The carboxyl-terminal 161 amino acids of the Na,K-ATPase alpha-subunit are sufficient for assembly with the beta-subunit. Chimeric cDNAs encoding regions of the Na,K-ATPase alpha-subunit and a sarcoplasmic reticulum Ca(2+)-ATPase were constructed and expressed together with the avian Na,K-ATPase beta-subunit cDNA in COS-1 cells to determine which regions of the alpha...

Mingot, Jé-Manuel.; Vega, S.; Maestro, B.; Sanz, Jús.M.; Nieto, M.Angela., 2009: Characterization of Snail nuclear import pathways as representatives of C2H2 zinc finger transcription factors. Snail proteins are C(2)H(2) class zinc finger transcription factors involved in different processes during embryonic development, as well as in several adult pathologies including cancer and organ fibrosis. The expression of Snail transcription fa...

D.Costa Lima, A., 1937: Other Flies with Larvae that attack Coccids. Descriptions are given of two additional Diptera the larvae of which attack Coccids in Brazil . One is a Drosophilid, Pseudiastata brasiliensis, sp. n., attacking Pseudococcus brevipes, Ckll., on Eriochloa punctata, and the other is an unnamed Ant...

Nieto, M.; Frade, J.M.; Sancho, D.; Mellado, M.; Martinez-A.C.; Sánchez-Madrid, F., 1997: Polarization of chemokine receptors to the leading edge during lymphocyte chemotaxis. Leukocyte migration in response to cell attractant gradients or chemotaxis is a key phenomenon both in cell movement and in the inflammatory response. Chemokines are quite likely to be the key molecules directing migration of leukocytes that invol...