geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Remnant lipoprotein cholesterol and triglyceride reference ranges from the Framingham Heart Study


, : Remnant lipoprotein cholesterol and triglyceride reference ranges from the Framingham Heart Study. Clinical Chemistry 44(6 Pt 1): 1224-1232

Remnants of triglyceride-rich lipoproteins of both intestinal and liver origin are considered atherogenic, but they have been difficult to isolate and measure. An assay has been developed that allows the measurement of remnant-like particle cholesterol (RLP-C) and triglyceride (RLP-TG). RLP-C and RLP-TG concentrations were measured in >3000 fasting plasma samples obtained from participants in exam cycle 4 of the Framingham Offspring Study and stored at -80 degrees C. After exclusions, comparisons were made for 2821 samples (1385 women, 1436 men; mean age, 52 years). For women, the mean RLP-C and RLP-TG values were 0.176 +/- 0.058 mmol/L (6.8 +/- 2.3 mg/dL) and 0.204 +/- 0.159 mmol/L (18.1 +/- 14.1 mg/dL), respectively; for men, the mean values were 0.208 +/- 0.096 mmol/L (8.0 +/- 3.7 mg/dL) and 0.301 +/- 0.261 mmol/L (26.7 +/- 23.1 mg/dL), respectively. Women had significantly lower RLP-C and RLP-TG values (P <0.0001) than men; premenopausal women had significantly lower values than postmenopausal women (P <0.0001); and younger subjects (<50 years) had significantly lower values than older individuals (P <0.0001). The 75th percentile values for RLP-C and RLP-TG were 0.186 mmol/L (7.2 mg/dL) and 0.225 mmol/L (19.9 mg/dL), respectively, for women, and 0.225 mmol/L (8.7 mg/dL) and 0.346 mmol/L (30.6 mg/dL) for men. These data provide reference ranges for use in the evaluation of RLP-C and RLP-TG as potential indicators of risk for coronary heart disease.

US$29.90

PMID: 9625046


Other references

Sternat, T.; Katzman, M.A., 2016: Neurobiology of hedonic tone: the relationship between treatment-resistant depression, attention-deficit hyperactivity disorder, and substance abuse. Anhedonia, defined as the state of reduced ability to experience feelings of pleasure, is one of the hallmarks of depression. Hedonic tone is the trait underlying one's characteristic ability to feel pleasure. Low hedonic tone represents a re...

Wentz, D.K., 1988: Continuing medical education: developments at the American Medical Association. Journal of Continuing Education in the Health Professions 9(1): 55-57

Rottensten, K., 1961: Inbreeding and relationship in the Jersey breed in Denmark.. A study of four-line pedigrees for 142 bulls and 382 cows showed that during the period 1915-56 the percentage of inbreeding was 0.27 per generation and the inter se relationship was 4.6%. The highest relationship of a single animal to the breed w...

Finnerty, G.T.; Roberts, L.S.; Connors, B.W., 1997: Sensory deprivation increases short-term depression of layer IV-II excitatory synapses in rat somatosensory cortex. Society for Neuroscience Abstracts 23(1-2): 574

Verzhbitskaia, N.I., 1968: Regeneration of stomach muscles following mechanical trauma in different periods of radiation sickness. Radiobiologiia 8(4): 529-534

Dunlop, A.L.; Logue, K.; Thorne, C., 2016: Maternal Health Risk Assessment and Behavioral Intervention in the NICU Setting Following Very Low Birth Weight Delivery. NlmCategory="UNASSIGNED">Objectives To investigate whether maternal health risk assessment and behavioral intervention in the neonatal intensive care unit (NICU) improves women's health care seeking and health behaviors following...

Petrak R.M.; Goodman L.J.; Segreti J.; Kaplan R.L.; Trenholme G.M., 1985: In vitro activity of antimalarial agents against enteric pathogens. Clinical Research 33(4): 847A

Ng, C.Fook.Sheng.; Stickley, A.; Konishi, S.; Watanabe, C., 2016: Ambient air pollution and suicide in Tokyo, 2001-2011. Some evidence suggests an association may exist between the level of air pollution and suicide mortality. However, this relation has been little studied to date. The current study examined the association in Tokyo, Japan. Suicide mortality data fo...

Davidson, A.J.; Shrivastava, P.P.; Jamsen, K.; Huang, G.H.; Czarnecki, C.; Gibson, M.A.; Stewart, S.A.; Stargatt, R., 2006: Risk factors for anxiety at induction of anesthesia in children: a prospective cohort study. In children anxiety at induction of anesthesia is a common and important aspect of the psychological impact of anesthesia and surgery. Previous studies examining risk factors for increased anxiety have found contradictory results. This may be due...

Brimacombe, G.G., 1995: CMA and divisions consider payment options. Cmaj 152(8): 1184-1185