+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Short-term efficacy of domestic gliclazide against noninsulin-dependent diabetes mellitus in 112 patients

, : Short-term efficacy of domestic gliclazide against noninsulin-dependent diabetes mellitus in 112 patients. Zhongguo Yiyao Gongye Zazhi 28(1): 23-26

Domestic gliclazid (1) was used to treat 112 patients with noninsulin-dependent diabetes mellitus (NIDDM). The other 93 were treated with imported product (2) as control. The daily oral dose of 1 ranged from 20 to 240 (111.1 +- 64.8) mg. After 2-3 months of treatment, mean fasting and 2-h postprandial blood glucose, plasma fibrinogen, urine glucose excretion and glucohemoglobin levels reduced significantly, glucose tolerance was elevated, serum insulin levels in fasting and after glucose loading increased appreciably, disorder of lipid metabolism was improved in 1 group. The effective dose of 1 was lower than that of 2. The efficacy and bioavailability of 1 were higher than that of 2.


Other references

Beck, H.; Hacker, H., 1983: Stilbina olympica Dierl & Povolny, 1970 Beschreibung des bisher unbekannten Weibchens und der Praimaginalstadien (Lepidoptera, Noctuidae). Mitteilungen Muenchener Entomologischen Gesellschaft, 73: 1-14

Borsari, B., 2014: Universal prevention for alcohol use disorders: 1940-2014. Universal prevention programs are intended to prevent or delay the onset of alcohol use disorders in the general population. This article reviews research on universal prevention programs for alcohol use published over the last 75 years. A literat...

Sharrock, P.; Fiallo, M.; Nzihou, A.; Chkir, M., 2009: Hazardous animal waste carcasses transformation into slow release fertilizers. Because of the need to address disposal of materials infected with pathogens new regulations have come into effect for the transport and disposal of dead farm animals or carcasses. For precautionary reasons, disposal to landfill, composting, bioga...

Bennett, J.H. ., 1983: Natural selection, heredity and eugenics, including selected correspondence of R.A. Fisher with Leonard Darwin and others. Unknown

Walz, C.; Gerlach, K.L.; Siranii, F., 1988: Ossifying fibroma of the maxilla--course, surgical treatment and prosthodontic aftercare. Deutsche Zahnarztliche Zeitschrift 43(3): 373-375

Mai, W.; Chen, D.; Li, X., 2012: Antioxidant Activity of Rhizoma Cibotii in vitro. The paper tried to systematically investigate the in vitro antioxidant activity of Rhizoma Cibotii (RC) for the first time. The methanol extract from RC (MERC) was prepared then systematically investigated by various antioxidant assays, including:...

Slezak F.A.; Thow G.B., 1987: Combined ligation injection treatment of hemorrhoids. A method of combined band ligation and sclerosant injection of internal hemorrhoids is described.

van Middelkoop, M.; van Rijn, R.M.; Verhaar, J.A.N.; Koes, B.W.; Bierma-Zeinstra, S.M.A., 2012: Re-sprains during the first 3 months after initial ankle sprain are related to incomplete recovery: an observational study. What are prognostic factors for incomplete recovery, instability, re-sprains and pain intensity 12 months after patients consult primary care practitioners for acute ankle sprains? Observational study. One hundred and two patients who consulted th...

Kohli, V.; Velosa, J.; Sterioff, S.; Munn, S.R., 1995: Prophylaxis for cytomegalovirus in pancreas transplant recipients using intravenous ganciclovir. Transplantation Proceedings 27(6): 2993-2993

Meilland, Ml, 1989: Rose plant--Meitifran variety. A new and distinct variety of rose plant of the Miniature Class is provided which forms in abundance highly attractive bicolored very double blossoms. The blossoms are white in coloration and bear bengal rose edges. The plant has glossy foliage, r...