+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Soluble serum interleukin-2 receptor, interleukin-6 and interleukin-1a in patients with endometriosis and in controls

, : Soluble serum interleukin-2 receptor, interleukin-6 and interleukin-1a in patients with endometriosis and in controls. Archives of Gynecology & Obstetrics 255(3): 107-112

The aim of this study was to verify to what extent danazol alters cell-mediated immunity. To this end, cell-mediated immunity was studied in 10 infertile patients with endometriosis and in 10 normal controls. Nonspecific parameters studied included serum SIL-2R, IL-6 and IL-1a levels. We also investigated the effect of treatment with Danazol on the levels of SIL-2R, IL-6 and IL-1a in women with endometriosis. Blood SIL-2R, IL-6 and IL-1a levels were measured in endometriotic women before treatment, during the last fifteen days of a 6-months course of Danazol and three months after treatment. Only one blood sample was taken from 10 women without endometriosis. SIL-2R, IL-6 and IL-1a levels were higher in women with endometriosis before treatment compared with controls. Administration of the drug significantly reduced the levels of SIL-2R (P lt 0.001), IL-6 (P lt 0.05) and IL-1a (P lt 0.01). Our findings suggest that endometriosis is a condition which induces a rise in interleukin levels. Danazol also appears significantly to reduce endometriosis - associated autoimmune abnormalities.


PMID: 7979562

DOI: 10.1007/bf02390936

Other references

Gerhard Lee C., 1985: Porosity development in the Mississippian pisolitic limestones of the Mission Canyon Formation, Glenburn Field, Williston Basin, North Dakota. Pages 191-205 1985

Fang Xiaomin; Mou Yunzhi; X.X.aoxia, 1987: Quartz grain surface features of the Maxian Mountain in the Lanzhou area and environment identification. Bingchuan Dongtu = Journal of Glaciology and Cryopedology 9(3): 250-255

Berstein A.; Bernauer I.; Marx R.; Geurtsen W., 1992: Human cell culture studies with dental metallic materials. The compatibility of cast non-alloyed titanium and eight dental castable alloys (precious, low noble, non-precious) was determined by means of human primary oral fibroblasts derived from the attached gingiva and the periodontium. Furthermore, cast...

Mulder, K.; Hagens, N.; Fisher, B., 2011: Burning water: a comparative analysis of the energy return on water invested. While various energy-producing technologies have been analyzed to assess the amount of energy returned per unit of energy invested, this type of comprehensive and comparative approach has rarely been applied to other potentially limiting inputs su...

Staude, J., 1987: Ergebnisse mehrjahriger Brutbestandsaufnahmen von Greifvogeln im Weserbergland. Vogelkundliche Berichte aus Niedersachsen, 192: 37-45

Brun, C., 1951: On tubular nephritis (lower nephron nephrosis) and its treatment. Four cases following acute diarrhoea. This paper is mainly a review, with numerous references; 4 cases are described in detail. Conservative treatment is advocated, with careful control of fluid balance, gradual correction of electrolyte disturbances, and an ample supply of energy, wi...

Radu, D.; Brodin, E.; Weber, G.; Lindefors, N., 2001: Delayed stress-induced increase in tissue level of cholecystokinin in rat prefrontal cortex: Modulation by microdialysis probe implantation and systemic ketamine. In the brain, the neuropeptide cholecystokinin (CCK) appears to be involved in the mediation of stress responses. Here we provide new evidence that mild stress induces long-term changes in CCK-like immunoreactivity (CCK-LI) in the prefrontal corte...

Thompson, C.M.; Wolf, J.C.; Elbekai, R.H.; Paranjpe, M.G.; Seiter, J.M.; Chappell, M.A.; Tappero, R.V.; Suh, M.; Proctor, D.M.; Bichteler, A.; Haws, L.C.; Harris, M.A., 2015: Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy. Lifetime exposure to high concentrations of hexavalent chromium [Cr(VI)] in drinking water results in intestinal damage and an increase in duodenal tumors in B6C3F1 mice. To assess whether these tumors could be the result of a direct mutagenic or...

Zhao, F.; Huang, F.; Tang, M.; Li, X.; Zhang, N.; Amfilochiadis, A.; Li, Y.; Hu, R.; Jin, T.; Peng, C.; Wang, Q., 2012: Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells. We demonstrated previously that the activation of ALK7 (activin receptor-like kinase-7), a member of the type I receptor serine/threonine kinases of the TGF-β superfamily, resulted in increased apoptosis and reduced proliferation through suppress...

Peus, F., 1977: Fleas from Anatolia and Iran (Insecta: Siphonaptera). IXth contribution in the series 'Fleas of the Mediterranean region'. The results are presented of surveys of fleas on small mammals (including bats) by F. Spitzenberger in the Anatolia region of Turkey and in Iran in 1974-75. Notes are provided on the dates, places of capture, mammalian hosts, previous records and,...