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Susceptibility to desferrioxamines and other chelators of coagulase-negative staphylococci

, : Susceptibility to desferrioxamines and other chelators of coagulase-negative staphylococci. Zentralblatt fuer Bakteriologie 280(3): 304-311

A total of 233 staphylococci and micrococci belonging to 17 species were tested for their susceptibility to desferrioxamines B, G and E, respectively. Using an agar diffusion method on iron poor media, all of the S. epidermidis, 12 out of 22 S. hominis and 5 out of 22 S. capitis strains were susceptible to desferrioxamines. Among the S. capitis strains tested, two of them were susceptible to desferrioxamine E and resistant to desferrioxamines B and G. All other staphylococci and micrococci tested were resistant to desferrioxamines B, G and E. Different susceptibility to 5 mM ethylenediaminedi-(o-phenylacetic acid) as an artificial chelator demonstrated the existence of additional iron-supplying systems in staphylococci and micrococci.


PMID: 8167423

DOI: 10.1016/S0934-8840(11)80591-8

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