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The reactivity of microvessels and macrovessels of the arterial bed in rats with renovascular hypertension


, : The reactivity of microvessels and macrovessels of the arterial bed in rats with renovascular hypertension. Fiziologicheskii Zhurnal SSSR Imeni I M Sechenova 77(9): 224-231

In rats with experimental hypertension, mesenteric artery revealed a hypersensitivity to noradrenaline whereas aorta did not differ from normal values of this parameter. The sensitivity of femoral artery was lowered. The microarterioles of hypertensive animals manifested a lower sensitivity to noradrenaline as well. This data suggests that arterial vessels manifest a regional heterogeneity of their functional properties in chronic birenal renovascular hypertension.

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