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Trichosporon beigelli infection in AIDS patients undergoing antifungal prophylaxis: Report of two cases

, : Trichosporon beigelli infection in AIDS patients undergoing antifungal prophylaxis: Report of two cases. Journal de Mycologie Medicale 3(3): 169-171

The major opportunistic fungal infections in AIDS patients are caused by Candida albicans (oral-oesophageal candidiasis and other forms) and by Cryptococcus neoformans. Antifungal prophylaxis is attempted in order to avoid relapses. However, the appearance of unusual fungal infections in AIDS patients, such as those cause by Trichosporon beigelii, attest that the prophylaxis is insufficient to prevent systemic mycosis, even though T. beigelii, in our two cases, was sensitive in vitro to ketoconazole. The here reported cases of AIDS-related T. beigelii infections, previously recognized in neutropenic leukemic patients, shows that this agent is a dangerous pathogen in immuno-suppressed HIV positive patients too.


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