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Cloning and sequencing of an acidic phospholipase A-2 from Trimeresurus mucrosquamatus venom


, : Cloning and sequencing of an acidic phospholipase A-2 from Trimeresurus mucrosquamatus venom. Journal of the Chinese Biochemical Society 23(1): 53-58

The major acidic phospholipase A-2 (PLA-2) was purified from the venom of Trimeresurus mucrosquamatus. Its complete primary structure was solved by automated N-terminal sequencing and sequencing of its cloned cDNA. The purified enzyme has been reported to be edema-inducing and anticoagulating. Its amino acid sequence identity to the acidic PLA-2 from T. flavorviridis is 92%.

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