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Extracellular glutamate increases in the lateral hypothalamus during meal initiation, and GABA peaks during satiation: microdialysis measurements every 30 s


, : Extracellular glutamate increases in the lateral hypothalamus during meal initiation, and GABA peaks during satiation: microdialysis measurements every 30 s. Behavioral Neuroscience 117(2): 222-227

Glutamate injected into the lateral hypothalamus can initiate eating, and gamma-aminobutyric acid (GABA) can stop it. This leads to the hypothesis that glutamate inputs are active at the beginning of a meal, and GABA is released at the end. To test this theory, the authors used microdialysis to sample glutamate and GABA simultaneously before, during, and after a meal. Food-deprived rats ate a meal of chow. Glutamate increased during the first third of the meal, then decreased to below baseline while the rats were still eating. GABA also increased at the start of the meal but continued rising and peaked during the last third of the meal. Glutamate may drive a hypothalamic system for eating, and GABA may oppose it. Reprinted by permission of the publisher.

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PMID: 12708518


Other references

Pan, Y.; Meng, B.; Zhang, H.; Cao, W.; Wang, H.; Bi, C.; Liu, F.; Sun, B.; Hao, X.; Ai, W.Z.; Fu, K., 2013: Low incidence of Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly in Tianjin, northern China. The purpose of this study was to examine the incidence of Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma of the elderly in a representative northern Chinese population. Overall, 212 cases of primary diffuse large B-cell lymphoma w...

Picha, J.P.chova, D.N.votny, L.S.arda, J.M.ka, J., 1984: Secretion of the luteinizing hormone and prolactin in cows after parturition and induced lactation. Biologizace a chemizace zivocisne vyroby veterinaria0(3): 279-288

Barr, Djs, 1986: Allochytridium expandens rediscovered: morphology, physiology and zoospore ultrastructure. Allochytridium expandens Salkin is a monocentric chytrid. The incipient sporangium enlarges from the germ tube and the sporangium has 1-3 discharge papillae or tubes which are distinctly operculate. Allochytridium expandens grows in media containi...

Ringshausen, F.C.; Heyer, C.M.; Schultze-Werninghaus, G.; Rohde, G., 2010: Dyspnea and dysphagia as the primary manifestation of a rare congenital vascular anomaly in an elderly lady: left pulmonary artery sling. Pneumologie 63(11): 662-663

Kim, B.Soo.; Kim, J.Young.; Song, C.Hyun.; Kim, H.Youn.; Lee, W.Ju.; Lee, S-Jong.; Kim, D.Won., 2012: Light-emitting diode laser versus pulsed dye laser-assisted photodynamic therapy in the treatment of actinic keratosis and Bowen's disease. Dermatologic Surgery 38(1): 151-153

Farronato, G.P.; Santoro, F.; Loiaconi, G., 1982: Mesiodens and surgical-orthodontic treatment. Mondo Ortodontico 7(2): 9-17

Gritsiuk, A.I.; Dybenko, R.S.; Chuvikina, V.T., 1986: Ambulatory care for patients with rheumatic diseases. Vrachebnoe Delo: 4-7

Bertke, E.M., 1963: Renal Function During The Course Of Eimeria Tenella Infection. Renal clearance studies, using uric acid as a marker, were made on white leghorn chickens infected orally with oocysts of Eimeria tenella. Three dosage levels were used: 40,000, 80,000, and 100,000 oocysts. In addition, for comparative study, two...

Calvert, S.A.; Hoskins, E.M.; Fong, K.W.; Forsyth, S.C., 1987: Etiological factors associated with the development of periventricular leukomalacia. Prenatal, intrapartum and postnatal factors are compared between 15 preterm infants, known to have periventricular leukomalacia (PVL) on ultrasound and 15 infants of similar birthweight and gestation who ultrasonographically showed no evidence of...

Sissingh, G.; Tideman, P., 1960: The plant communities of the surroundings of Didam and Zevenaar. The vegetation map 125000 was carried out by the Nature Conservancy Department of the State Forest Service. It is a part of a collection of data which will be used for a comprehensive regional agricultural plan. About 40 plant communities have bee...