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Metabolic aspects of development of left ventricular myocardial hypertrophy in patients with essential hypertension

, : Metabolic aspects of development of left ventricular myocardial hypertrophy in patients with essential hypertension. Kardiologiya 35(12): 27-30

In 54 patients with essential hypertension and left ventricular hypertrophy most important characteristics of the fibrinolytic system - activity of tissue type plasminogen activator inhibitor and content of tissue type plasminogen activator antigen - were determined. Significant correlation was found between degrees of left ventricular hypertrophy and content of tissue type plasminogen activator antigen. This correlation allowed to suggest participation of this component of the fibrinolytic system in processes of myocardial damage in hypertension. It can also be used for explanation of well known association of left ventricular hypertrophy with atherothrombotic complications.


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