geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The end of the beginning for pluripotent stem cells


, : The end of the beginning for pluripotent stem cells. Nature 414(6859): 92-97

Part of a special section explaining the fundamentals of stem cell biology. Pluripotent stem cells represent an incredible resource for the repair of diseased or damaged tissues in our bodies and promise to open a new door into the embryonic development of our species. These stem cells can be expanded seemingly indefinitely in culture, maintaining a normal karyotype, and have the potential to generate every cell type in the body. Recent advances suggest that, if certain major hurdles are overcome, pluripotent stem cells derived from human embryos could be used to treat a wide variety of human diseases, especially those in which specific cell types have been lost or disabled. In addition, studies of these cells may, for the first time, afford an understanding of how a human embryo grows and develops into a new individual, and how the process can go awry. The opportunity comes with great responsibility, but also inspires great awe.

US$19.90

PMID: 11689953

DOI: 10.1038/35102154


Other references

Bennett, R.; Cooke, R., 2005: Control of bovine TB: preferences of farmers who have suffered a TB breakdown. Cattle farmers in England, UK, whose herds had experienced a tuberculosis (TB) breakdown were surveyed concerning their views on different policy options for controlling bovine TB. On-farm personal interviews were conducted on 151 randomly selecte...

Poulose K.P.; Kapcar A.J.; Reba R.C., 1976: False positive iodine 125 fibrinogen test. Angiology 27(4): 258-261

Chang, P.W.; Hay, B.A.; Stagnitti, G.E., 1994: Advances in maltol/ethyl maltol applications. Abstracts of Papers American Chemical Society 208(1-2): AGFD 135

Putnam, S., 2002: Cases from the Osler Medical Service at Johns Hopkins University. B(12) deficiency. American Journal of Medicine 112(3): 230-231

Biswas, S.; Zhang, B.; Li, Z.; Wu, M.; Doebber, T.; Moller, D.E., 1999: Effect of insulin sensitizing agents on insulin receptor substrate-1 serine phosphorylation. FASEB Journal 13(7): A1489, April 23

Kettleman, K., 1998: Controlling bone pain. How to keep nausea and oversedation out of the picture. Nursing 28(11): 22-22

Price, J.A.; Grunfeld, E.; Barnes, P.J.; Rheaume, D.E.; Rayson, D., 2010: Inter-institutional pathology consultations for breast cancer: impact on clinical oncology therapy recommendations. Despite recommendations favouring review of cancer pathology specimens for patients being treated at an institution other than the one that produced the initial pathology report, data regarding discordance rates and their potential clinical impact...

Kanaan, N.; Bachman, L.A.; McGregor, C.G.A.; Griffin, M.D., 2003: Porcine antigen presenting cells produce soluble adjuvants that stimulate B cells within and across the species. Interactions between porcine antigen presenting cells (pAPCs) and host lymphocytes may be important in cellular and humoral rejection of porcine organ xenografts. To investigate the role of pAPCs in the activation of xenogeneic lymphocytes, porcin...

Bean, AE., 1973: On the distribution of some lycaenid and hesperid butterflies. Journal Northampt nat Hist Soc, 36: 884-895

Leĭkin, I.N.; Novodarova, G.N.; Kolosova, E.M.; Vol'pin, M.E., 1979: Role of planar cobalt chelate complexes as shunting agents in the electron transport chain of mitochondria. It was shown that planar cobalt chelate complexes catalyze oxidation of NADH and hexahydroubiquinole Q4H2 by air oxygen. The most active agent--perchlorate of the cobalt complex 1, 2, 3, 7, 8, 12, 13, 17, 18, 19-decamethyloctadehydrocorrin--is cap...