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A study on the relationship between genetic and environmental factors of type 2 diabetes mellitus in humans


, : A study on the relationship between genetic and environmental factors of type 2 diabetes mellitus in humans. Zhonghua Yu Fang Yi Xue Za Zhi 36(3): 191-194

Objective: To study the relationship between the inheritable factor and environmental factors of type 2 diabetes mellitus in humans. Methods: A case-control study based on 154 type 2 diabetes mellitus and 130 healthy controls was carried out in Jiangsu Province in 1997. Results: The age, family history of diabetes mellitus, hypertension history, high waist/hip ratio (WHR), high systolic blood pressure, huge fetus history, and the genotype of beta3-adrenergic receptor (beta3-AR) were the risk factors of type 2 diabetes mellitus; while occupational physical activity was protective factor of type 2 diabetes mellitus. The risk for diabetes mellitus distinctly increased while genetic factor and obesity, beta3-AR mutation were coexisting. Conclusion: Type 2 diabetes mellitus is caused by the effect of both genetic and environmental factors.

US$29.90

PMID: 12410955


Other references

Antoine, J.C., 2002: Paraneoplastic peripheral neuropathies. Revue Neurologique 157(12): 1557-1560

Hulsemann, K.; Fleminger, A., 1975: Some aspects of copepodid development in the genus Pontellina Dana (Copepoda: Calanoida). Bulletin Mar Sci, 252: 174-185

Povoa, H.; Souza, A.C.; Teixeira, L.C.; Sargentelli, L., 1973: Plasmalogens in ischaemic heart disease. Acta Biologica et Medica Germanica 31(6): 897-898

Orr W.C.; Allen M.; Finn A.; Robinson M.G., 1988: Timing of evening meal and ranitidine administration on patterns of 24 hr intragastric ph. Annual Review of Chronopharmacology : 321-322

Gao, J.J.; Filla, M.B.; Fultz, M.J.; Vogel, S.N.; Russell, S.W.; Murphy, W.J., 1998: Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene. We have examined the role of Stat1alpha in the induction by LPS of the mouse inducible nitric oxide synthase (EC 1.14.13.39) gene. LPS induced both the tyrosine phosphorylation of Stat1alpha and the production of nitric oxide in a time- and dose-d...

Drumm, B.; Rhoads, J.M.; Stringer, D.A.; Sherman, P.M.; Ellis, L.E.; Durie, P.R., 1988: Peptic ulcer disease in children: etiology, clinical findings, and clinical course. The records of all children with peptic ulcer disease at the Hospital for Sick Children were retrospectively evaluated, excluding neonates, throughout a 5-year period. Only cases with a definite ulcer crater identified either at endoscopy or at su...

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Charmillot, P.J.; Frischknecht, M.L.; Schmid, A.; Hoehn, H., 1986: Control of the vine moth eupoecilia ambiguella hb. and the grape moth lobesia botrana den. and schiff by means of the ovicidal activity of the insect growth regulator igr fenoxycarb. Results are reported from various field trials against first and second generations of the vine and the grape moth in the Valais as well as in northern and western Switzerland. In most cases, applications with 0.0075% fenoxycarb were made at the b...

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