+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

An integrative approach to the treatment of obsessive-compulsive disorder

, : An integrative approach to the treatment of obsessive-compulsive disorder. Comprehensive Psychiatry 42(1): 24-31

We reviewed the research literature concerning the etiology and treatment of obsessive-compulsive disorder (OCD). Cognitive behavioral and neurobiological treatments were the two most frequently used treatment approaches. The majority of research on the treatment of OCD has focused on implementing these treatment approaches in isolation, rather than in combination, which has often resulted in a high symptom relapse rate. We focused on integrating the most effective elements of each treatment approach into a new treatment regimen. More specifically, the long-lasting benefits of cognitive behavioral therapy and the rapid symptom relief of neurobiological treatments are integrated in such a manner as to take full advantage of each, while at the same time controlling for the shortcomings of each treatment approach. It is proposed that this newly integrated treatment approach represents a superior treatment regimen, as compared with the combined treatment approaches currently used.


PMID: 11154712

DOI: 10.1053/comp.2001.19757

Other references

Ledgerwood, L.; Richardson, R.; Cranney, J., 2003: Effects of D-cycloserine on extinction of conditioned freezing. The present study tested the prediction that D-cycloserine (DCS), a partial N-methyl-D-aspartate agonist, would facilitate extinction of conditioned freezing in male Sprague-Dawley rats. Rats received 5 light-shock pairings (conditioning). The fol...

Smart, Re, 1989: Solar radiation interception as a guide to the design of horticultural plantings. II. Twenty years experience with grapevines. Acta Horticulturae 240: 87-94

Gu, F.; Aniento, F.; Parton, R.G.; Gruenberg, J., 1997: Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomes. In the present paper, we show that transport from early to late endosomes is inhibited at the restrictive temperature in a mutant CHO cell line (ldlF) with a ts-defect in epsilon coatomer protein (epsilonCOP), although internalization and recyclin...

Eaton D.L., 1985: Effects of various trace metals on the binding of cadmium to rat hepatic metallothionein determined by the cadmium hemoglobin affinity assay. Toxicology & Applied Pharmacology 78(1): 158-162

Houshian, S.; Larsen, M.S.; Holm, C., 2002: Missed injuries in a level I trauma center. Background: Major trauma presents major diagnostic and therapeutic problems. Any delay in providing the treatment necessary may lead to increased morbidity and mortality, prolonged length of hospital stay, and increased cost. This study was undert...

Leach, S.J.; Minasian, E.; Reichert, L.E., 1975: Bovine luteinizing hormone. Circular dichroism and thermal difference spectra. The circular dichroism of bovine luteinizing hormone in the far ultraviolet (200–240 nm) and near ultraviolet (240–320 nm) is reported as a function of pH, reduction and denaturation. The significance of side-chain ellipticity in the native an...

Kelly, B.S.; Levy, J.G., 1979: Purification of a protein associated with human bronchogenic squamous-cell carcinoma. A heteroantiserum raised in rabbits to extracts of human squamous-cell carcinoma of the lung which exhibited marked tumour specificity was used to monitor the fractionation and isolation of a tumour-associated component of the extract. KC1 extract...

Anonymous, 1999: Understanding the learning context. Nt Learning Curve 3(1): 12-15

Young, F.E., 1986: Health technology assessment. The current political framework: the U.S. perspective. Israel Journal of Medical Sciences 22(3-4): 173-178

Du, Y.; Guan, D-wei.; Zhao, R., 2004: An immunohistochemical study on the expression of caspase-3 in the skin wound healing. To investigate the expression of caspase-3 during skin wound healing and explore the applicability of caspase-3 to determination of wound age. The expression of caspase-3 were performed on 33 mice skin incised wounds at different posttraumatic int...