+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Blood pressure, cognitive functions, and prevention of dementias in older patients with hypertension

, : Blood pressure, cognitive functions, and prevention of dementias in older patients with hypertension. Archives of Internal Medicine 161(2): 152-156

The prevalence and incidence of degenerative and vascular dementias increase exponentially with age, from 70 years onward. In view of the increasing longevity of humans, both varieties are bound to evolve into a major problem worldwide. According to several longitudinal studies, hypertension appears to predispose individuals to the development of cognitive impairment and ensuing dementia, after a period varying from a few years to several decades. Antihypertensive drug treatment, according to preliminary evidence, may serve to reduce the rates of such events. Such findings await to be confirmed by formal therapeutic trials against a backdrop of "historical" observational sources.


PMID: 11176727

Other references

Frankenfield, K.N.; Powers, E.T.; Kelly, J.W., 2005: Influence of the N-terminal domain on the aggregation properties of the prion protein. Prion diseases appear to be caused by the aggregation of the cellular prion protein (PrPC) into an infectious form denoted PrPSc. The in vitro aggregation of the prion protein has been extensively investigated, yet many of these studies utilize tr...

Kawabata, H., 1966: Some therapeutic problems for cataracta traumatica and cataracta complicata. Nihon Ganka Kiyo 17(10): 958-959

Ortner, K.M., 2003: Production costs and export support: proceedings against Canada's milk export regime before the WTO. Canada's dairy marketing regime has been based on restricting supply through a quota system and division of production into categories attracting differentiated prices, such as for export or surplus milk. Setting low prices for the latter has...

Gadow, H., 1886: Reproduction of the Carapax in Tortoises. Journal of Anatomy and Physiology 20(Pt 2): 220-224

Wrathall, J.R.; Li, W.; Hudson, L.D., 1998: Myelin gene expression after experimental contusive spinal cord injury. After incomplete traumatic spinal cord injury (SCI), the spared tissue exhibits abnormal myelination that is associated with reduced or blocked axonal conductance. To examine the molecular basis of the abnormal myelination, we used a standardized...

Dobrynin, V.A., 1965: Main indices of intensity of dairy cattle breeding. Various standards for measuring intensity in cattle breeding are compared, of which capital input per cow seems to be the most reliable. In addition various economic problems of Soviet animal husbandry (fodder cost, labour input, seasonal producti...

Garcia J.E.; Braza F., 1987: Activity rhythms and use of space of a group of aotus azarae in bolivia during the rainy season. A group of Aotus azarae living in an island forest in the Beni region of Bolivia was observed for ten nights during the rainy season of 1985. The three members of the group, an adult male, an adult female, and the young of the year, spent 49.4% of...

Villar, V.Hugo.; Vögler, O.; Barceló, F.; Martín-Broto, J.; Martínez-Serra, J.; Ruiz-Gutiérrez, V.; Alemany, R., 2016: Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma. Several important biological activities have been attributed to the pentacyclic triterpene ursolic acid (UA), being its antitumoral effect extensively studied in human adenocarcinomas. In this work, we focused on the efficacy and molecular mechani...

Wang, Y.; Perchellet, E.M.; Ward, M.M.; Lou, K.; Hua, D.H.; Perchellet, J-Pierre.H., 2005: Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones. Since synthetic analogs of 1,4-anthraquinone (AQ code number), such as AQ8, AQ9 and AQ10, can trigger cytochrome c release without caspase activation and retain their ability to induce apoptosis in multidrug-resistant (MDR) tumor cells, fluorescen...

Edwards, S.C.; Kovacs, K.F.Iv; Vidal, E.; Severence, E., 1999: Characterization of calcineurin expressed in Limulus photoreceptors. IOVS 40(4): S214, March 15