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Can molluscs biosynthesize typical sponge metabolites? The case of the nudibranch Doriopsilla areolata

, : Can molluscs biosynthesize typical sponge metabolites? The case of the nudibranch Doriopsilla areolata. Tetrahedron 57(42): 8913-8916, 15 October

The first study on the biosynthesis of terpenoid metabolites in the porostome nudibranch Doriopsilla areolata is described herein. The de novo origin of two different groups of bi- and tri-cyclic sesquiterpenes, exhibiting opposite A/B ring junctions, has been clearly demonstrated by in vivo incorporation of labeled mevalonate. Surprisingly, metabolites of both series have been previously reported to co-occur in a sponge of genus Dysidea, that could be included in the diet of the nudibranch.


DOI: 10.1016/s0040-4020(01)00876-6

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