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Circadian intraocular pressure variation with beta-blockers


, : Circadian intraocular pressure variation with beta-blockers. Acta Ophthalmologica Scandinavica 77(5): 500-503, Oct

Purpose: To investigate circadian intraocular pressure variation in patients treated with topical beta-blockers as monotherapy. Method: Circadian IOP curves were measured on 25 patients (47 eyes) treated with topical beta-blockers. IOP was recorded 4 times during the day and twice at night. All IOP measurements were taken using a non-contact tonometer. Results: IOP at night was significantly higher than IOP during the day. Thirty-four percent exhibited an increase in IOP of more than 5 mmHg at night, and 15% exhibited an increase of 10-18 mmHg at night. The median range of circadian IOP variation was 7 mmHg. Determined separately by day, the range of IOP variation was 4 mmHg. Conclusion: Patients treated with beta-blockers as monotherapy may experience greater variations in IOP than can be detected by conventional daytime IOP measurements.

US$19.90

PMID: 10551287

DOI: 10.1034/j.1600-0420.1999.770502.x


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