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Diabetic gustatory sweating successfully treated with topical glycopyrrolate: report of a case and review of the literature

, : Diabetic gustatory sweating successfully treated with topical glycopyrrolate: report of a case and review of the literature. Archives of Internal Medicine 159(8): 877-878

Background: Gustatory sweating is a more common manifestation of diabetes mellitus than is appreciated. It is a distressing problem that has been difficult to treat safely. Methods: Daily topical application of glycopyrrolate roll-on lotion was offered as an alternative to oral anti-cholinergic agents to an 87-year-old woman with longstanding type 2 diabetes mellitus who complained of profuse sweating after eating. Results: Gustatory sweating was relieved by application of glycopyrrolate and reappeared when the glycopyrrolate was briefly withdrawn to confirm its therapeutic effect. Conclusion: For moderate to severe symptoms of diabetic gustatory sweating, topical application of glycopyrrolate is safe, effective, well tolerated, and convenient.


PMID: 10219935

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