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Efecto del bromuro de ipratropio sobre la broncoconstriccion por histamina en sujetos con obstruccion cronica al flujo aereo


, : Efecto del bromuro de ipratropio sobre la broncoconstriccion por histamina en sujetos con obstruccion cronica al flujo aereo. Medicina (Buenos Aires) 61(3): 262-266

Ipratropium bromide (IB), a quaternary derivative of atropine has been extensively recommended as the first bronchodilator to be tried in chronic obstructive pulmonary disease (COPD). Despite the large information concerning IB use, a controversy still persists about the lack of non bronchodilator effects (preventive) of inhaled IB. Therefore, the purpose was: to study the effects of IB (80 mug) on histamine-induced bronchoconstriction in moderate airway obstruction due to COPD.

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