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Efectos de sustratos competitivos y de la insulina sobre la captacion y el destino metabolico de la glucosa en corazon perfundido de ratas dislipemicas

, : Efectos de sustratos competitivos y de la insulina sobre la captacion y el destino metabolico de la glucosa en corazon perfundido de ratas dislipemicas. Medicina (Buenos Aires) 60(6): 923-930

Rats chronically fed (15 weeks) a sucrose-rich diet (SRD) developed hypertriglyceridemia (hyperTg), increased plasma free fatty acids (FFA), impaired glucose homeostasis and insulin insensitivity. An increase of Tg and glycogen (Gly) in heart muscle was also observed. HyperTg with altered glucose metabolism could have profound effects on myocardial glucose utilization.


Other references

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Yap, L.Fah.; Velapasamy, S.; Lee, H.Min.; Thavaraj, S.; Rajadurai, P.; Wei, W.; Vrzalikova, K.; Ibrahim, M.Hafez.; Khoo, A.Soo-Beng.; Tsao, S.Wah.; Paterson, I.C.; Taylor, G.S.; Dawson, C.W.; Murray, P.G., 2015: Down-regulation of LPA receptor 5 contributes to aberrant LPA signalling in EBV-associated nasopharyngeal carcinoma. Undifferentiated nasopharyngeal carcinoma (NPC) is a highly metastatic disease that is consistently associated with Epstein-Barr virus (EBV) infection. In this study, we have investigated the contribution of lysophosphatidic acid (LPA) signalling...

Chung, S.H.; Allen, T.W.; Hoyles, M.; Kuyucak, S., 1999: Permeation of ions across the potassium channel: Brownian dynamics studies. The physical mechanisms underlying the transport of ions across a model potassium channel are described. The shape of the model channel corresponds closely to that deduced from crystallography. From electrostatic calculations, we show that an ion...

Frank, D.A.; Beeghly, M.; Rose Jacobs, R.; Knight, W.G.ant; Posner, M., 2000: Level of prenatal cocaine exposure and school age language development. Pediatric Research 47(4 Part 2): 309A, April

Forrester, J.S.; Milne, S.B.; Ivanova, P.T.; Brown, H.Alex., 2004: Computational lipidomics: a multiplexed analysis of dynamic changes in membrane lipid composition during signal transduction. Recent successes in defining the roles of lipids in cell signaling have stimulated greater interest in these versatile biomolecules. Until recently, analysis of these molecules at the species level has required labor-intensive techniques. The deve...

Chatel, M.; Dechanet, R.; Notteghem, J.L.; Rakotonirainy, R., 1981: Breeding rainfed rice in Madagascar. Pedigree selection for yield, reduced height, earliness, drought resistance and good horizontal resistance to Pyricularia oryzae was carried out on 22 crosses from 12 varieties, both local and introduced, at four localities using two generations p...

Segretain, G.; Verge, J.; Drieux, H.; Mariat, F.; Paraf, A.; Labie, C.; Theron, B., 1956: Mastitis caused by Cryptococcus neoformans. The authors report a case of bovine mastitis caused by Cryptococcus neoformans. The affected quarter was enlarged and hard, and there was mild oedema of the hindquarters associated with loss of skin and hair. The little milk obtainable from the qu...

Pande, H.K.; Narkhede, N.N., 1972: Tillering behaviour and grain yield of lowland rice in relation to nitrogen fertilization. In a pot trial during Aug.-Dec. 1966 to study the response of rice cv. Taichung 65 to different rates of N given in split applications applied by different methods at various growth stages, tiller emergence was earlier with than without N. In comp...