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Effect and safety of pseudoephedrine-dextromethorphan drops

, : Effect and safety of pseudoephedrine-dextromethorphan drops. Zhongguo Xinyao yu Linchuang Zazhi 22(4): 195-198, Apr

AIM: To evaluate the effect and safety of pseudoephedrine-dextromethorphan drops in treating cough and rhinocleisis symptoms caused by common cold. METHODS: A multi-center randomized control clinical trial Was used. One hundred and forty-two patients were divided into two groups. The trial group of seventy-one patients (M 38, F 33; age (16+-s 9)mo) took psudoehedrine-dextromethorphan drops and the control group of seventy-one patients (M 41, F 30; age (18+-10) mo) took pseudoephedrine, chlorphenamine and dextromethorphan solution. Each patient took medicine according to the age of the moon. The medicine was taken qid for 5 d. RESULTS: The antitussive and releasing rhinocleisis rate after d 5 was 75% and 87%, respectively. The adverse reaction rate of the trial group was 1%, no significant difference between two groups. No serious adverse reactions appeared. CONCLUSION: Pseudophedrine-dextromethorphan drops in treating cough and rhinocleisis symptoms caused by common cold is safe and effective without any obvious adverse reactions.


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