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Effect of (-)-cis-3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-trans-4-(3-hydroxypropyl)cyclohexanol (CP55,940) on intracellular Ca2+ levels in human osteosarcoma cells


, : Effect of (-)-cis-3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-trans-4-(3-hydroxypropyl)cyclohexanol (CP55,940) on intracellular Ca2+ levels in human osteosarcoma cells. Chinese Journal of Physiology 45(3): 95-100

The study was undertaken to explore the effect of CP55,940 ((-)-cis-3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-trans-4-(3-hydroxypropyl)cyclohexanol), a drug commonly used as a CB1/CB2 cannabinoid receptor agonist, on intracellular free Ca2+ levels ((Ca2+)i) in MG63 human osteoblast-like epithelial cells. (Ca2+)i was measured in suspended cells by using the fluorescent dye fura-2 as an indicator.

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