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Experimental study on assessment of left ventricular systolic function in early diabetic cardiomyopathy by Doppler tissue imaging

, : Experimental study on assessment of left ventricular systolic function in early diabetic cardiomyopathy by Doppler tissue imaging. Zhongguo Chaosheng Yixue Zazhi 19(6): 401-404

Objective: To evaluate the developmental course of left systolic ventricular function in early diabetic cardiomyopathy by Doppler tissue imaging (DTI). Methods: Cardiac function was examined with DTI in rabbits of 2, 4, 6 and 8 weeks after intravenous injection into auricular marginal vein with 65 mg/kg of streptozotocin (STZ). The motion of lateral wall and posterior interventricular septum at mitral annulus was estimated with PW-DTI. The parameters such as systolic peak velocity (Sa), preejection period (PEP), local ejection time (ET) and systolic mean velocity (Vm) of four various portions in mitral annulus were determined. The killed rabbit hearts were examined microscopically after echo cardiography at 2, 4, 6 and 8 week in respective 4 groups. Results: STZ-induced diabetic rabbits menifested the systolic dysfunction as early as at 6 weeks. Conclusions: DTI can display early systolic dysfunction of diabetic cardiomyopathy in STZ-induced diabetic rabbits without coronary disease.


Other references

Siegal T.; Siegal T.; Shohami E., 1987: The effect of dexamethasone and indomethacin on spinal cord prostanoids and edema in neoplastic epidural compression. Neurology 37(3 SUPPL 1): 311

Kato, H.; Suzuki, T., 1970: Amino acid sequence of bradykinin-potentiating peptide isolated from the venom of Agkistrodon halys blomhoffi. Proc. Japan Acad.: 46: 176-181

Inage, H.; Koyama, A.; Narita, M.; Tojo, S., 1985: Effects of the antiplatelet agents, dipyridamole and dilazep dihydrochloride, on in vivo platelet function and proteinuria. Nihon Jinzo Gakkai Shi 27(9): 1261-1270

Carmo Sousa, L.D.; Uden, N.V.n, 1958: Studies on the contaminstion of yoghurt by yeasts.. Of 103 samples of yoghuit from 4 Lisbon factories, 70.8% were heavily contaminated with Candida psgiidotropicalis and Candide krvsei and slight ly contaminated with Candida mycodgrma. The yeasts multiplied durmg storage even at +or- 3 C and were,...

Tjia H.D.; Almashoor Syed Sheikh, 1996: The Bentong Suture in southwest Kelantan, Peninsular Malaysia. A newly constructed dirt road between Kampung Raja, Cameron Highlands, and Pulai, Ulu Kelantan, crosses the Bentong Suture which here is at least 18 km wide. The eastern border zone of the suture consists of bedded chert containing an internal low...

Lianxing Wen, 2000: Intense seismic scattering near the Earth's core-mantle boundary beneath the Comoros Hotspot. Geophysical Research Letters 27(22): 3627

Kristiansen, T.Mechlenborg.; Antoft, R., 2016: Patient education as a status passage in life - An ethnographic study exploring participation in a Danish group based patient education programme. In this paper, we apply the theory of status passage to the empirical field of group-based patient education. On the basis of ethnographic fieldwork carried out in the context of a local Danish patient education programme aimed at people diagnosed...

Terashima, I.; Kohda, K., 1998: Inhibition of human O6-alkylguanine-DNA alkyltransferase and potentiation of the cytotoxicity of chloroethylnitrosourea by 4 - -2,6 -diamino-5- pyrimidine derivatives and analogues. A series of 4(6)-(benzyloxy)-2,6(4)-diamino-5-(nitro or nitroso)pyrimidine derivatives and analogues of which 4(6)-benzyloxy groups were replaced with a (2-, 3-, or 4-fluorobenzyl)oxy or (2-, 3-, or 4-pyridylmethyl)oxy group, was synthesized. The...

Swift, S.; Throup, J.P.; Williams, P.; Salmond, G.P.; Stewart, G.S., 1996: Quorum sensing: a population-density component in the determination of bacterial phenotype. In bacteria, a network of cellular transduction mechanisms integrate signals from the bacterial environment to control gene expression, and thereby the bacterial phenotype. 'Quorum sensing' describes one such signalling mechanism in resp...

Heirtzler James R.; L.P.chon Xavier, 1965: Crustal structure of the mid-ocean ridges; 3, Magnetic anomalies over the mid-Atlantic ridge. The magnetic anomaly pattern over the mid-Atlantic ridge between latitude 60 degrees N. and 42 degrees S. was studied, using 58 magnetic profiles. The basic pattern shows a large anomaly, about 1,000 km wide, centered on the axis of the ridge. Thi...