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Indian red scorpion (Mesobuthus tamulus concanesis, Pocock) venom prolongs repolarization time after refactoriness of the compound action potential of frog sciatic nerve in vitro through calcium dependent mechanism


, : Indian red scorpion (Mesobuthus tamulus concanesis, Pocock) venom prolongs repolarization time after refactoriness of the compound action potential of frog sciatic nerve in vitro through calcium dependent mechanism. Indian Journal of Experimental Biology 36(11): 1108-1113

Effects of Indian red scorpion (M. tamulus concanesis; MBT) venom on the compound action potential (CAP) of sciatic nerve in vitro were examined. MBT venom (0.1-6.0 mug/ml) prolonged the repolarization time and refractory period of the CAP in a concentration-dependent manner with maximal potentiation occurring at 6 mug/ml (about 100-200 times of the initial).

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