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Induction of indora expression in pole cells by the mesoderm is required for female germ-line developmenin Drosophila melanogaster


, : Induction of indora expression in pole cells by the mesoderm is required for female germ-line developmenin Drosophila melanogaster. Development (Cambridge) 126(5): 1023-1029, March

In many animal groups, the interaction between germ and somatic line is required for germ-line development. In Drosophila, the germ-line precursors (pole cells) formed at the posterior tip of the embryos migrate toward the mesodermal layer where they adhere to the dorsolateral mesoderm, which ensheaths the pole cells to form the embryonic gonads. These mesodermal cells may control the expression of genes that function in pole cells for their development into germ cells. However, such downstream genes have not been isolated. In this study, we identify a novel transcript, indora (idr), which is expressed only in pole cells within the gonads. Reduction of idr transcripts by an antisense idr expression caused the failure of pole cells to produce functional germ cells in females. Furthermore, we demonstrate that idr expression depends on the presence of the dorsolateral mesoderm, but it does not necessarily require its specification as the gonadal mesoderm. Our findings suggest that the induction of idr in pole cells by the mesodermal cells is required for germ-line development.

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PMID: 9927602


Other references

Spyrka, M.; Cehula, M.; Kuzma, F.; Hano, V., 1984: Trends in the economic differentiation of cooperative farm development in the West Slovakia region; some factors of economic differentiation in cooperative farms of Eastern Slovakia. Mobilization of internal reserves without the need for more external resources is required for the further development of socialist agricultural production. At present there is much scope for production expansion but it is limited by the availabil...

Hopf, U.; Zum-Bueschenfelde, K.H.M.; Dierich, M.P., 1976: Demonstration of binding sites for immuno globulin g fc and complement c 3 on isolated hepatocytes. Isolated hepatocytes from rabbits with experimental acute serum sickness showed immune complexes bound to the hepatocellular membrane with a coarse granular fluorescent pattern. In vitro preformed immune complexes (BSA [bovine serum albumin]-anti-...

Kompanje, E.J.O., 1995: Differences between spondylo-osteomyelitis and spondylosis deformans in small odontocetes based on museum material. In this article the differences between spondylo-osteomyelitis, which is an infective disease, and spondylosis deformans, a degenerative condition, in small odontocetes are discussed. Some cases of spondylo-osteomyelitis are described from museum-...

Sakun, O.F., 1960: Chemical nature and significance of the inclusions in the oocytes of osseous fish. Arkh Anat Gistol I Embriol 38(1): 38-42

Wallace, L.J.; Partlow, L.M.; Ferrendelli, J.A., 1978: Comparison of levels of amp in highly purified and mixed primary cultures of neurons and nonneuronal cells from embryonic chick sympathetic ganglia. Primary cultures containing .gtoreq. 99% neurons, .gtoreq. 99% non-neuronal cells (glia), or both cell types were prepared from the sympathetic ganglia of 12 day chick embryos. Levels of cyclic[c]AMP in the non-neuronal cells (.apprx. 14 pmol/mg p...

Terhaar, C.J., 1955: On the cytology of certain cells of the cestode, Hydatigera laemae-formis (Batsch, 1786). Terhaar, studying the cytology of Hydatigera taemaefprrms has demonstrated mitochondria and Golgi material in the parenchymal cells and in tile muscle cells of the parenchyma. Mitonchondria and a round nuclear inclusion which stained brilliant red...

Miller, A.; Siffel, C.; Correa, A., 2010: Residential mobility during pregnancy: patterns and correlates. Information on patterns and correlates of residential mobility can be important in studies of environmental factors and birth outcomes. The objective of this study was to describe residential mobility patterns and possible sociodemographic correla...

Muller, R.A.; Stephenson, E.J.; Mast, T.S., 1978: Radioisotope dating with an accelerator: a blind measurement. The age of a sample of carbon dioxide has been determined by accelerating the carbon with a cyclotron and detecting the carbon-14 ions in the beam. Nitrogen-14 was eliminated as a background through the use of a range-separation technique. To avoi...

Philip, K.M., 1980: Producing more rubber. The supply/demand crisis in the natural rubber industry in the recent past has raised questions about India's ability to produce enough rubber to meet future demand. With the oil crisis tending to tighten availability of synthetic rubber, per...

Ferrari, F.; Goldstein, I.; Nieszkowszka, A.; Elman, M.; Marquette, C-Hugo.; Rouby, J-Jacques., 2003: Lack of lung tissue and systemic accumulation after consecutive daily aerosols of amikacin in ventilated piglets with healthy lungs. Anesthesiology 98(4): 1016-1019