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Localization of paclitaxel in suspension culture of Taxus chinensis

, : Localization of paclitaxel in suspension culture of Taxus chinensis. Journal of Microbiology & Biotechnology 11(3): 458-462, June

The localization of paclitaxel was investigated in suspension culture cells of Taxus chinensis. Over 93% of the cell-associated paclitaxel were detected throughout the entire culture period. Intracellular localization of paclitaxel over the culture time was analyzed further by cell fractionation for days 21 and 42. Paclitaxel contents in intracellular organelles were decreased at day 42, while the content in the cell wall fraction was increased at day 42 compared to the value for day 21. The localization of paclitaxel in the cell wall was confirmed by using the immunocytochemical method with the aid of a confocal laser scanning microscope.


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Hills John M., 1961: Discussion of Correlation of Permian formations of North America, by Dunbar, C. O., and others. Discussion of GeoScience Abstracts 3-1133. The equivalence of the San Andres dolomite of the Central Basin platform and shelf areas with the Blaine and Dog Creek of the Panhandle, southeastern Colorado, and Kansas seems certain. Perrinites occurs...

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Cussen,V.A., 2008: Enforcement of transport regulations the EU as case study. The European Union (EU) has a more comprehensive legislation for animal welfare during transport than anywhere else in the world. However, legislation must be adequately enforced to ensure compliance and, thereby, satisfactory levels of animal wel...

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