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Long-term intraspinal infusions of opioids with a new implantable medication pump

, : Long-term intraspinal infusions of opioids with a new implantable medication pump. Arzneimittel-Forschung 49(6): 489-493

Experiences with long-term intraspinal infusion of opioid drugs using the new implantable medication pump VIP 30 in patients with chronic non-malignant pain are reported. During a 19-month period 10 patients with chronic pain - mainly mixed nociceptive-neuropathic pain - underwent implantation of the medication pump for long-term treatment. The mean follow-up period was 9.5 months. Pain relief was classified as very good in 22.2%, good in 44.4%, moderate in 22.2% and poor in 11.1%. In 88.9% of the cases the patients stated they would undergo the same procedure again. Technical problems (catheter dislocation) developed in 1/10 patients could be surgically corrected. One pump including catheter was explanted because of an infected seroma within the pocket area. Long-term intrathecal application of opioids with the VIP 30 pumps is an effective and safe treatment in patients with chronic non-malignant pain.


PMID: 10417863

DOI: 10.1055/s-0031-1300448

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