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Nosocomial infections occurring during receipt of circulatory support with the paracorporeal ventricular assist system

, : Nosocomial infections occurring during receipt of circulatory support with the paracorporeal ventricular assist system. Clinical Infectious Diseases 35(11): 1308-1315

This retrospective study sought to report the spectrum of infections in a homogenous group of 39 patients who underwent implantation of the Thoratec paracorporeal ventricular assist device system (Thoratec Laboratories) in an emergency setting. Thirty-one of the 39 patients developed a total of 99 nosocomial infections (attack rate, 79.5%; incidence, 4.9 per 100 support-days). The lungs were the most frequently involved site (31.3%), and coagulase-negative Staphylococcus species were the pathogens most frequently isolated (16.2%). Infected patients required more transfusions and chest surgical revisions, as well as a longer duration of mechanical ventilation and a longer stay in the intensive care unit, compared with uninfected patients. Cox regression analysis revealed that chest surgical revision was the only independent risk factor for infection at any site (odds ratio, 2.6; 95% confidence interval, 1.2-5.7). There was no significant effect of infection on heart transplantation rate and overall survival.


PMID: 12439792

DOI: 10.1086/343825

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Gold, E.B.; Lasley, B.; Crawford, S.L.; McConnell, D.; Joffe, H.; Greendale, G.A., 2007: Relation of daily urinary hormone patterns to vasomotor symptoms in a racially/ethnically diverse sample of midlife women: study of women's health across the nation. The associations of urinary pregnanediol-glucuronide (PdG) levels and menstrual bleeding and their modification of associations of other risk factors with vasomotor symptoms (VMS) are examined. Daily urine samples were collected for 1 menstrual cy...

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Almeida, F.Aécio.; Bruno, Débora.S.; Faiz, S.; Hinrichs, B.; Eapen, G.A.; Bashoura, L., 2011: Hemothorax treated with indwelling tunneled pleural catheter: are all hemothoraces the same?. Historically, patients presenting with a hemothorax of any cause have been treated with tube thoracostomy. We describe 2 patients with a hemothorax successfully treated with an indwelling tunneled pleural catheter. Our cases may suggest a new trea...

Kanazawa, Y.; Kuramata, T., 1972: Laboratory and clinical studies on lividomycin, with special reference to in vitro antimicrobial activity, active levels in body fluids and sensitivity disc method. Japanese Journal of Antibiotics 25(6): 367-374

Anonymous, 1976: Log jam breaks. British Medical Journal 1(6001): 60-60

Li, Z.; Gong, W-bin.; Liu, H-mei.; Cui, Z-lin.; Huang, H-bo.; Sun, X-yong., 2003: Intravenous contrast imaging in diagnosis of acute renal allograft rejection: a comparative study with color flow Doppler imaging. To assess the value of intermittent contrast second harmonic imaging (SHI) incorporating acoustic densitometry in the diagnosis of acute renal allograft rejection in comparison with color Doppler flow imaging (CDFI) for determining the resistance...

Siffre, M.A.; Dedonder, R., 1967: Enzymes intervening in the formation of nucleotide-sugars in Rhizobium japonicum. Comptes Rendus Hebdomadaires des Seances de L'academie des Sciences. Serie D: Sciences Naturelles 264(10): 1346-1349

Dariyerli, N.; Toplan, S.; Akyolcu, M.Can.; Hatemi, H.; Yigit, G., 2004: Erythrocyte osmotic fragility and oxidative stress in experimental hypothyroidism. The present study was planned to explain the relation between erythrocyte osmotic fragility and oxidative stress and antioxidant statue in primary hypothyroid-induced experimental rats. Twenty-four Spraque Dawley type female rats were divided into...

Chen, Y.; Campbell, S.L.; Dokholyan, N.V., 2007: Deciphering protein dynamics from NMR data using explicit structure sampling and selection. Perhaps one of the most prominent realizations of recent years is the critical role that protein dynamics plays in many facets of cellular function. While characterization of protein dynamics is fundamental to our understanding of protein functio...

Bischoff, A.; Bucher, M.; Gekle, M.; Sauvant, C., 2015: Differential effect of COX1 and COX2 inhibitors on renal outcomes following ischemic acute kidney injury. We have previously shown that 1 mg/kg indomethacin improves expression and functionality of renal organic anion transporters Oat1 and Oat3 after renal ischemia and furthermore improves renal outcome after ischemia. As we detected differential effe...