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Plasma cortisol levels in elderly female subjects with Alzheimer's disease: A cross-sectional and longitudinal study


, : Plasma cortisol levels in elderly female subjects with Alzheimer's disease: A cross-sectional and longitudinal study. Brain Research 881(2): 241-243, 27 October

We investigated the plasma cortisol levels at a fasting state in elderly female Alzheimer's disease (AD), vascular dementia (VD), and non-demented subjects (n=66, 28 and 21, respectively). Twenty-eight AD subjects were followed for 40 months. The plasma cortisol levels in AD and VD subjects were significantly higher than those of non-demented subjects at baseline. In AD subjects in relatively early stages of the disease [Mini-Mental State Examination (MMSE)], at baseline, high plasma cortisol led to rapid declines in MMSE scores over a 40-month period.

US$19.90

PMID: 11036168

DOI: 10.1016/s0006-8993(00)02847-x


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