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Relationship between obesity and plasma lipoproteins in adolescents with different apolipoprotein E phenotypes


, : Relationship between obesity and plasma lipoproteins in adolescents with different apolipoprotein E phenotypes. Biomedical Research (Aligarh) 11(1): 93-102, Jan -April

The association between body mass index (BMI), regional fat distribution and the plasma lipoproteins were determined in samples of 16 to17-year-old adolescents (n=144). The subjects were chosen from the schools in Kuala Lumpur, Klang Valley where the total community of 15 to19 year old adults is estimated to be 80,000 by the bureau of statistics. Covariates (race and sex) adjusted mean value of body mass index (weight in kilograms / height in meters2) and the regional fat indices (skin fold thickness) was found to be significantly higher (p < 0.05) in the epsilon3/epsilon4 group, than in the epsilon3/epsilon2 group. The waist: hip ratio (w/h ratio) and the triceps did not show any significant differences between the genotypic groups. The race and sex adjusted mean values of the total and low density lipoprotein (LDL) cholesterol were significantly lower (p< 0.05) in the e3/e2 group than in the e3/e3 group. In the epsilon3/epsilon3 group, covariates adjusted partial correlation coefficients showed a significant association (0.001

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