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Successful steroid therapy for cefdinir-induced acute tubulointerstitial nephritis with progressive renal failure


, : Successful steroid therapy for cefdinir-induced acute tubulointerstitial nephritis with progressive renal failure. Internal Medicine 40(2): 114-117

A 58-year-old woman was admitted to our hospital because of renal dysfunction that continued to progress even after withdrawal of cefdinir, the presumed cause of acute renal failure. Renal histologic findings included interstitial fibrosis accompanied by moderate lymphocytic infiltration, and tubular atrophy with reduced numbers of epithelial cells. Mesangial cells and glomerular basement membranes were nearly normal. Scintigraphy with 67gallium disclosed diffuse abnormal accumulation in both kidneys. A lymphocyte stimulation test with cefdinir was positive. The patient was diagnosed with acute tubulointerstitial nephritis caused by cefdinir. Serum creatinine concentrations continued to rise after withdrawal of the drug, but steroid therapy was effective in normalizing renal function.

US$19.90

PMID: 11300142

DOI: 10.2169/internalmedicine.40.114


Other references

Romasenko L.P., 1983: Study of the biology of megachile centuncularis. Representatives of Megachile are important pollinators of various agricultural plants. M. centuncularis is one of the most effective alfalfa pollinators. The species is widespread in almost all natural geographic zones of the Ukrainian SSR [USSR]....

Adamson, A.H.; Newell, D.W.; Castle, M.E., 1979: A comparison between supplements to silage of high digestibility offered to dairy cows. Grass silage containing crude protein and digestible organic matter at 180 and 660 g/kg DM, resp., was offered to 42 dairy cows for 20 wk in a self-feeding system. In addition, supplements of either mineralized barley or barley + groundnut with cr...

Zharov, Av, 1980: Current problems of metabolic pathology in highly productive livestock. Patomorfologiia patogenez i diagnostika boleznei sel'skokhoziaistvennykh zhivotnykh Vsesoiuznaia ordena Lenina i ordena Trudovogo Krasnogo Znameni akademiia sel'skokhoziaistvennykh nauk imeni V I Lenina redaktsionnaia kollegiia V P Shishkov otvetstvennyi redaktor i dr

Greener, M., 1993: Gene therapy: the dawn of a revolution. Gene therapy offers the hope of effective treatment for thousands of people with genetic diseases, such as diabetes and muscular dystrophy. Early research looks promising, but doubts about its safety remain.

Camargo, M.B.P.; Santos, M.A.; Pedro Junior, M.J.; Fahl, J.I., 2007: Agrometeorological model for monitoring and predicting coffee (Coffea arabica L.) productivity in Sao Paulo State, Brazil. A model to reliably monitor and assess agrometeorological impact on coffee yield just before the beginning of the maturation growth stage is proposed. Historical phenological observations and yield data were collected from adult coffee plantations...

Matolog, N.M.; Wolfman, E.F., 1977: Primary repair of colonic injuries: a clinical evaluation. Fifty-seven patients with colonic injuries were treated by primary repair with or without exteriorization. Forty-six of these had other associated major intra-abdominal, intrathoracic, and musculoskeletal injuries. All had minimal contamination of...

Salvini-Plawen, LV., 1985: Early evolution and the primitive groups. Unknown

Barrow, M.; Fitzsimmons, J.S., 1984: A new syndrome. Short limbs, abnormal facial appearance, and congenital heart defect. American Journal of Medical Genetics 18(3): 431-433

Andenmatten, R., 1981: Recovery of germs dried on surfaces with the collector by Thran. Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale B, Hygiene 173(6): 446-451

Stark, H., 1991: Otoplasty using the CO2 laser. Laryngo- Rhino- Otologie 70(11): 652-652