geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The prevalence of antibiotic resistance among gram negative bacilli from Intensive Care Units in Oman


, : The prevalence of antibiotic resistance among gram negative bacilli from Intensive Care Units in Oman. Saudi Medical Journal 20(5): 373-377

Objectives: This study aims to investigate antibiotic consumption and the prevalence of antibiotic resistance among gram-negative bacteria in Intensive Care Units. Methods: Antibiotic consumption during the study period was recorded. Ninety six gram-negative bacteria from patients in the intensive care units were identified and tested for susceptibilities to 12 antibiotics. Ceftazidime-resistant Escherichia coli and Klebsiella spp. were further tested for production of extended spectrum beta-lactamases. Results: Antibiotic consumption, mostly penicillins and cephalosporins was equivalent to 605 treatment days per 100 hospital discharges. The commonest isolates were Pseudomonas aeruginosa, followed by Klebsiella spp. and Escherichia coli, mostly recovered from sputum and blood. Ciprofloxacin and imipenem, showed the highest in-vitro activity, inhibiting 94% and 92% of the strains. Thirty six percent of the strains were susceptible to ceftriaxone, 40% to cefotaxime and 78% to ceftazidime. Piperacillin and piperacillin/tazobactam inhibited 73% and 82% of strains. Aminoglycosides' activity was similar to that of piperacillin/tazobactam. Forty one percent of Klebsiella spp. were resistant to all cephalosporins and aztreonam. Imipenem resistance occurred with Pseudomonas spp, Acinetobacter spp. and Stenotrophomonas maltophilia. Conclusion: Overuse of antibiotics could be behind this high rate of drug resistance. Rational prescribing of antibiotics should be encouraged through educational programs, surveillance and audit.

US$29.90

PMID: 27631291


Other references

Delforge P., 1990: Contribution to the knowledge of the orchids of southwest cyprus mediterranean sea and remarks on some mediterranean species. Recent studies on critical groups of Orchidaceae in the south-west of Cyprus and somewhere else result in new systematic views. Observations on the genus Orchis lead to the recognition of the specific level for O. troodi from Cyprus and O. sitiaca...

Crous, P.W.; Quaedvlieg, W.; Sarpkaya, K.; Can, C.; Erkılıç, A., 2014: Septoria-like pathogens causing leaf and fruit spot of pistachio. Several species of Septoria are associated with leaf and fruit spot of pistachio (Pistacia vera), though their identity has always been confused, making identification problematic. The present study elucidates the taxonomy of the Septoria spp. ass...

Pena, C.; Marafiotti, R.; Bernhardt, Y.F., 1993: Argentina Strategic, theoretical and methodological criteria to evaluate and plan massive prevention. IXTH INTERNATIONAL CONFERENCE ON AIDS AND THE IVTH STD WORLD CONGRESS IXth International Conference on AIDS in affiliation with the IVth STD World Congress : 839

Herbener, T.E., 1996: Ultrasound physics: principles of ultrasonography. Gastrointestinal Endoscopy 43(2 Pt 2): S4-S6

Quentin, J.C.; Barre, N., 1976: Description and life history of Tetrameres (Tetrameres) cardinalis sp. n. A new species of Spirurid Nematode Tetrameres (Tetrameres) cardinalis n. sp. parasite of a Cardinal: Richmondia cardinalis is described. This Tetrameres shows primitive cephalic structures, 33 to 43 pairs of somatic spines in male, spicules of une...

Fishberg, E.H.; Dolin, B.T., 1930: The intermediate metabolism of foreign sugars. A method is given for the separate determination of xylose and galactose in the presence of dextrose in 02 cc. of blood. The reducing nonfermentable fraction of the blood is remarkably constant in normal human beings, amounting to about 28 [plus o...

Srivastava, A.; Mathias, A.; Yachha, S.K.; Aggarwal, R., 2016: Occult hepatitis B infection in children with chronic liver disease. Occult hepatitis B infection (OBI) may adversely affect the outcome of patients with chronic liver disease (CLD). There are no data on OBI and CLD in children. This study determined the prevalence and effect of OBI in HBsAg-negative CLD children....

Osipov, N.A.; Sobko, N.I., 1984: High-quality practical training for the young military physician. Voenno-Meditsinskii Zhurnal: 16-19

Lipinsky, D.; Gershengorn, M.C.; Oron, Y., 1995: Contribution of response kinetics to the response pattern: studies of responses to thyrotropin-releasing hormone in Xenopus oocytes. In Xenopus oocytes injected with total rat pituitary GH3 cell RNA, thyrotropin-releasing hormone (TRH) causes the activation of the inositol lipid transduction pathway and the induction of chloride conductance via calcium-activated channels (Oron...

Desai, B.H., 1983: Financial structure of cotton textile mills in Ahmedabad. The book is a condensed and partially revised version of the author's doctoral thesis. Its main chapters cover: background; concept and theory of financial structure; proprietorship funds; non-proprietorship funds: secured loans and unsecured...