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Trisomy 13 in one fetus from a twin gestation after intracytoplasmic sperm injection. A case report


, : Trisomy 13 in one fetus from a twin gestation after intracytoplasmic sperm injection. A case report. Journal of Reproductive Medicine 46(5): 497-498

BACKGROUND: Intracytoplasmic sperm injection (ICSI) is an assisted reproductive technique used in the treatment of severe male factor infertility. Reports of chromosomal aberrations in some fetuses conceived following ICSI have raised concern that the technique may contribute to the development of genetic disease. CASE: Trisomy 13 occurred in one of twin fetuses of a 28-year-old woman who underwent ICSI. This case is unique because it is the first reported one of an autosomal trisomy complicating one fetus from a twin gestation conceived by ICSI. It is also the first case describing an autosomal trisomy following ICSI in a woman under the age of 35. CONCLUSION: Chromosomal abnormalities associated with ICSI may be accounted for by factors other than advanced maternal age. Chromosomal aberrations may be related to the procedure itself. Therefore, patients should be advised of the possibility of aneuploidy in association with ICSI, and genetic amniocentesis should be considered regardless of maternal age.

US$29.90

PMID: 11396380


Other references

Drew, R.; Miners, J.O., 1984: The effects of buthionine sulphoximine (BSO) on glutathione depletion and xenobiotic biotransformation. Buthionine sulphoximine (BSO) is an inhibitor of gamma-glutamylcysteine synthetase (gamma-GCS) and, consequently lowers tissue glutathione (GSH) concentrations. In fed male C3H mice, liver and kidney GSH levels were depleted by BSO in a dose depen...

John K.Hall, 2006: GEBCO centennial special issue; charting the secret world of the ocean floor; the GEBCO project 1903-2003. This special issue of Marine Geophysical Researches presents five papers dealing with GEBCO, the General Bathymetric Chart of the Oceans, which celebrated its Centennial in April 2003, hosted by the International Hydrographic Bureau and the Princi...

Medical Sickness, W., 2011: Protect your most important asset: yourself. You have worked hard to get to where you are today, so it would be foolish to risk it all by not ensuring your income and your assets are protected. Cars, homes and valuables are among the first things we insure, but many people forget about prote...

Jelicks, L.A.; Siri, F.M., 1995: Intracellular free sodium in compensated and failing hypertrophied guinea pig hearts. Biophysical Journal 68(2 PART 2): A412

Moulton, K.S., 1992: Global competition in canned peaches, pears and related products. Volume 1: analysis of competitive issues. This is the first volume of a two volume series of reports on global competition in the canned fruit industry. This volume collects ten articles published between 1988 and 1992 that analyse various aspects of competition affecting California'...

Flabeau, F.; Breger, P.R., 1951: Three cases of embolism of arteries of the extremities; embolectomy; cure. Memoires. Academie de Chirurgie 77(31-32): 985-988

Herczeg, T.; Kun, L., 1961: Experiences in the field of acute pancreatitis. Zentralblatt für Chirurgie 86: 1957-1963

Riemekasten, G.; Gundelach, B., 2013: Mentor program: feedback of participating students : response to the German Society for Rheumatology congress in Bochum. Zeitschrift für Rheumatologie 72(1): 89-90

Elliott D.N.; Frazier L.A.; Hayden R.C.Jr, 1971: Relational and absolute cues in auditory discrimination by rhesus monkeys. Perception & Psychophysics 10(4B): 278-282

Awwiller David N.; Mack Lawrence E., 1991: Diagenetic modification of Sm-Nd model ages in Tertiary sandstones and shales, Texas Gulf Coast. Geology (Boulder) 19(4): 311-314